Abstract
The dopamine D2 receptor gene is a candidate gene for schizophrenia. We screened three exons of this gene for mutations in a large sample of schizophrenics. delusional patients and healthy controls. No structural changes were found, thus suggesting that psychopathology is not related to DNA alterations in the DRD2 gene.
| Original language | English |
|---|---|
| Pages (from-to) | 1-3 |
| Number of pages | 3 |
| Journal | Neuropsychobiology |
| Volume | 26 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 1992 |
Keywords
- Delusional disorder
- Denaturing gradient gel electrophoresis
- DNA
- Dopamine D<inf>2</inf> receptor gene
- Polymerase chain reaction
- Polymorphisms
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Neuropsychology and Physiological Psychology
- Neuroscience(all)
- Psychology(all)
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Catalano, M., Nobile, M., Novelli, E., & Smeraldi, E. (1992). Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients. Neuropsychobiology, 26(1-2), 1-3. https://doi.org/10.1159/000118888