Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients

Marco Catalano, Maria Nobile, Emanuela Novelli, Enrico Smeraldi

Research output: Contribution to journalArticle

Abstract

The dopamine D2 receptor gene is a candidate gene for schizophrenia. We screened three exons of this gene for mutations in a large sample of schizophrenics. delusional patients and healthy controls. No structural changes were found, thus suggesting that psychopathology is not related to DNA alterations in the DRD2 gene.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalNeuropsychobiology
Volume26
Issue number1-2
DOIs
Publication statusPublished - 1992

Keywords

  • Delusional disorder
  • Denaturing gradient gel electrophoresis
  • DNA
  • Dopamine D<inf>2</inf> receptor gene
  • Polymerase chain reaction
  • Polymorphisms
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychology(all)

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