Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients

Marco Catalano; Maria Nobile; Emanuela Novelli; Enrico Smeraldi

doi:10.1159/000118888

Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D₂ receptor gene in schizophrenic and delusional patients

Marco Catalano, Maria Nobile, Emanuela Novelli, Enrico Smeraldi

Research output: Contribution to journal › Article › peer-review

Abstract

The dopamine D₂ receptor gene is a candidate gene for schizophrenia. We screened three exons of this gene for mutations in a large sample of schizophrenics. delusional patients and healthy controls. No structural changes were found, thus suggesting that psychopathology is not related to DNA alterations in the DRD₂ gene.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	Neuropsychobiology
Volume	26
Issue number	1-2
DOIs	https://doi.org/10.1159/000118888
Publication status	Published - 1992

Keywords

Delusional disorder
Denaturing gradient gel electrophoresis
DNA
Dopamine D<inf>2</inf> receptor gene
Polymerase chain reaction
Polymorphisms
Schizophrenia

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry
Neuropsychology and Physiological Psychology
Neuroscience(all)
Psychology(all)

Access to Document

10.1159/000118888

Cite this

Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D₂ receptor gene in schizophrenic and delusional patients. / Catalano, Marco; Nobile, Maria; Novelli, Emanuela et al.

In: Neuropsychobiology, Vol. 26, No. 1-2, 1992, p. 1-3.

Research output: Contribution to journal › Article › peer-review

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