Use of T-SPOT.TB in latent tuberculosis infection diagnosis in general and immunosuppressed populations

Federica Piana, Luigi Rufio Codecasa, Rossella Baldan, Paolo Miotto, Maurizio Ferrarese, Daniela Maria Cirillo

Research output: Contribution to journalArticlepeer-review

Abstract

Immunosuppressed patients have a nine-fold greater risk of developing active tuberculosis (TB) disease given the latent TB infection than the general population. Few data are available on the predictivity of T-SPOT.TB in immuno-suppressed patients. We had a T-SPOT.TB determination and a TST from 197 immunosuppressed haematological patients and 324 community contacts of infectious TB cases. In the general population, TST was positive in 275 (84,9%), T-SPOT.TB in 167 (51.5%) (p

Original languageEnglish
Pages (from-to)286-290
Number of pages5
JournalNew Microbiologica
Volume30
Issue number3
Publication statusPublished - Jul 2007

Keywords

  • IGRA test
  • Immunosuppression
  • LTBI
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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