Abstract
Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.
Original language | English |
---|---|
Pages (from-to) | 207-215 |
Number of pages | 9 |
Journal | Recent Patents on Anti-Cancer Drug Discovery |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Cancer
- In vivo imaging
- Quantum dots
ASJC Scopus subject areas
- Oncology
- Cancer Research
- Pharmacology (medical)
- Drug Discovery