Use of the semiconductor nanotechnologies "quantum dots" for in vivo cancer imaging

Monica Ciarlo, Patrizia Russo, Alfredo Cesario, Sara Ramella, Gabriella Baio, Carlo E. Neumaier, Laura Paleari

Research output: Contribution to journalArticlepeer-review

Abstract

Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.

Original languageEnglish
Pages (from-to)207-215
Number of pages9
JournalRecent Patents on Anti-Cancer Drug Discovery
Volume4
Issue number3
DOIs
Publication statusPublished - 2009

Keywords

  • Cancer
  • In vivo imaging
  • Quantum dots

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Pharmacology (medical)
  • Drug Discovery

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