Use of the semiconductor nanotechnologies "quantum dots" for in vivo cancer imaging

Monica Ciarlo; Patrizia Russo; Alfredo Cesario; Sara Ramella; Gabriella Baio; Carlo E. Neumaier; Laura Paleari

doi:10.2174/157489209789206841

Use of the semiconductor nanotechnologies "quantum dots" for in vivo cancer imaging

Monica Ciarlo, Patrizia Russo, Alfredo Cesario, Sara Ramella, Gabriella Baio, Carlo E. Neumaier, Laura Paleari

Research output: Contribution to journal › Article › peer-review

Abstract

Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.

Original language	English
Pages (from-to)	207-215
Number of pages	9
Journal	Recent Patents on Anti-Cancer Drug Discovery
Volume	4
Issue number	3
DOIs	https://doi.org/10.2174/157489209789206841
Publication status	Published - 2009

Keywords

Cancer
In vivo imaging
Quantum dots

ASJC Scopus subject areas

Oncology
Cancer Research
Pharmacology (medical)
Drug Discovery

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abstract = "Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.",

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author = "Monica Ciarlo and Patrizia Russo and Alfredo Cesario and Sara Ramella and Gabriella Baio and Neumaier, {Carlo E.} and Laura Paleari",

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AU - Ciarlo, Monica

AU - Russo, Patrizia

AU - Cesario, Alfredo

AU - Ramella, Sara

AU - Baio, Gabriella

AU - Neumaier, Carlo E.

AU - Paleari, Laura

PY - 2009

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AB - Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.

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Use of the semiconductor nanotechnologies "quantum dots" for in vivo cancer imaging

Abstract

Keywords

ASJC Scopus subject areas

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