Use of Venovenous Extracorporeal Membrane Oxygenation as a Bridge to Urgent Lung Transplantation in a Case of Acute Respiratory Failure

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Abstract

Several transplant centers consider pretransplant extracorporeal membrane oxygenation (ECMO) as a contraindication for lung transplantation because of the poor outcomes. However, some technical improvements have changed the scenario; there is increasing evidence of ECMO efficacy as a bridge to lung transplantation. This report describes the successful use of venovenous ECMO as a bridge to an urgent bilateral lung transplantation and as treatment for primary graft dysfunction in a case of hyperacute pulmonary fibrosis in a 58-year-old man. Our experience demonstrated that ECMO, using Quadrox, supported respiratory functions for 28 days without any detrimental effects, serving as a successfully bridge to urgent lung transplantation.

Original languageEnglish
Pages (from-to)1345-1346
Number of pages2
JournalTransplantation Proceedings
Volume41
Issue number4
DOIs
Publication statusPublished - May 2009

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Extracorporeal Membrane Oxygenation
Lung Transplantation
Respiratory Insufficiency
Primary Graft Dysfunction
Pulmonary Fibrosis
Transplants
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Medicine(all)

Cite this

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abstract = "Several transplant centers consider pretransplant extracorporeal membrane oxygenation (ECMO) as a contraindication for lung transplantation because of the poor outcomes. However, some technical improvements have changed the scenario; there is increasing evidence of ECMO efficacy as a bridge to lung transplantation. This report describes the successful use of venovenous ECMO as a bridge to an urgent bilateral lung transplantation and as treatment for primary graft dysfunction in a case of hyperacute pulmonary fibrosis in a 58-year-old man. Our experience demonstrated that ECMO, using Quadrox, supported respiratory functions for 28 days without any detrimental effects, serving as a successfully bridge to urgent lung transplantation.",
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AU - Santambrogio, L.

AU - Nosotti, M.

AU - Palleschi, A.

AU - Tosi, D.

AU - Mendogni, P.

AU - Lissoni, A.

AU - Blasi, F.

AU - Rosso, L.

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