Usefulness of latent left ventricular dysfunction assessed by Bowditch Treppe to predict stress-induced pulmonary hypertension in minimally symptomatic severe mitral regurgitation secondary to mitral valve prolapse

Eustachio Agricola, Tonino Bombardini, Michele Oppizzi, Alberto Margonato, Matteo Pisani, Giulio Melisurgo, Eugenio Picano

Research output: Contribution to journalArticlepeer-review

Abstract

We assessed whether the presence of latent myocardial dysfunction, evaluated by echocardiographic derived force-frequency relationship (FFR) during exercise, predicts the appearance of stress-induced pulmonary hypertension in minimally symptomatic patients with severe mitral regurgitation (MR). Two groups of patients were identified: group I with normal (≤40 mm Hg) and group II with abnormal (>40 mm Hg) peak stress systemic pulmonary artery pressure. Group I had normal and upsloping FFR and group II had abnormal flat or biphasic FFR. Therefore, in patients with severe MR and apparently normal left ventricular function, the stress-induced pulmonary hypertension seems to be related to the presence of latent left ventricular dysfunction.

Original languageEnglish
Pages (from-to)414-417
Number of pages4
JournalThe American Journal of Cardiology
Volume95
Issue number3
DOIs
Publication statusPublished - Feb 1 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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