Usefulness of Predilation Before Transcatheter Aortic Valve Implantation

Matteo Pagnesi; Richard J. Jabbour; Azeem Latib; Hiroyoshi Kawamoto; Akihito Tanaka; Damiano Regazzoli; Antonio Mangieri; Claudio Montalto; Marco B. Ancona; Francesco Giannini; Alaide Chieffo; Matteo Montorfano; Fabrizio Monaco; Alessandro Castiglioni; Ottavio Alfieri; Antonio Colombo

doi:10.1016/j.amjcard.2016.04.018

Usefulness of Predilation Before Transcatheter Aortic Valve Implantation

Matteo Pagnesi, Richard J. Jabbour, Azeem Latib, Hiroyoshi Kawamoto, Akihito Tanaka, Damiano Regazzoli, Antonio Mangieri, Claudio Montalto, Marco B. Ancona, Francesco Giannini, Alaide Chieffo, Matteo Montorfano, Fabrizio Monaco, Alessandro Castiglioni, Ottavio Alfieri, Antonio Colombo

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Balloon predilation is historically considered a requirement before performing transcatheter aortic valve implantation (TAVI). As the procedure has evolved, it has been questioned whether it is actually needed, but data are lacking on mid-term outcomes. The aim of this study was to evaluate the effect of balloon predilation before TAVI. A total of 517 patients who underwent transfemoral TAVI from November 2007 to October 2015 were analyzed. The devices implanted included the Medtronic CoreValve (n = 216), Medtronic Evolut R (n = 30), Edwards SAPIEN XT (n = 210), and Edwards SAPIEN 3 (n = 61). Patients were divided into 2 groups depending on whether pre-implantation balloon aortic valvuloplasty (pre-BAV) was performed (n = 326) or not (n = 191). Major adverse cardiac and cerebrovascular events (MACCE) were primarily evaluated. Propensity score matching was used to adjust for differences in baseline characteristics and potential confounders (n = 113 pairs). In the overall cohort, patients without pre-BAV had a significantly higher MACCE rate at 30 days, driven by a higher incidence of stroke (0.3% pre-BAV vs 3.7% no-pre-BAV, p

Original language	English
Journal	The American Journal of Cardiology
DOIs	https://doi.org/10.1016/j.amjcard.2016.04.018
Publication status	Accepted/In press - Jan 21 2016

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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Pagnesi, M., Jabbour, R. J., Latib, A., Kawamoto, H., Tanaka, A., Regazzoli, D., Mangieri, A., Montalto, C., Ancona, M. B., Giannini, F., Chieffo, A., Montorfano, M., Monaco, F., Castiglioni, A., Alfieri, O., & Colombo, A. (Accepted/In press). Usefulness of Predilation Before Transcatheter Aortic Valve Implantation. The American Journal of Cardiology. https://doi.org/10.1016/j.amjcard.2016.04.018

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title = "Usefulness of Predilation Before Transcatheter Aortic Valve Implantation",

abstract = "Balloon predilation is historically considered a requirement before performing transcatheter aortic valve implantation (TAVI). As the procedure has evolved, it has been questioned whether it is actually needed, but data are lacking on mid-term outcomes. The aim of this study was to evaluate the effect of balloon predilation before TAVI. A total of 517 patients who underwent transfemoral TAVI from November 2007 to October 2015 were analyzed. The devices implanted included the Medtronic CoreValve (n = 216), Medtronic Evolut R (n = 30), Edwards SAPIEN XT (n = 210), and Edwards SAPIEN 3 (n = 61). Patients were divided into 2 groups depending on whether pre-implantation balloon aortic valvuloplasty (pre-BAV) was performed (n = 326) or not (n = 191). Major adverse cardiac and cerebrovascular events (MACCE) were primarily evaluated. Propensity score matching was used to adjust for differences in baseline characteristics and potential confounders (n = 113 pairs). In the overall cohort, patients without pre-BAV had a significantly higher MACCE rate at 30 days, driven by a higher incidence of stroke (0.3% pre-BAV vs 3.7% no-pre-BAV, p ",

author = "Matteo Pagnesi and Jabbour, {Richard J.} and Azeem Latib and Hiroyoshi Kawamoto and Akihito Tanaka and Damiano Regazzoli and Antonio Mangieri and Claudio Montalto and Ancona, {Marco B.} and Francesco Giannini and Alaide Chieffo and Matteo Montorfano and Fabrizio Monaco and Alessandro Castiglioni and Ottavio Alfieri and Antonio Colombo",

year = "2016",

month = jan,

day = "21",

doi = "10.1016/j.amjcard.2016.04.018",

language = "English",

journal = "American Journal of Cardiology",

issn = "0002-9149",

publisher = "Elsevier Inc.",

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T1 - Usefulness of Predilation Before Transcatheter Aortic Valve Implantation

AU - Pagnesi, Matteo

AU - Jabbour, Richard J.

AU - Latib, Azeem

AU - Kawamoto, Hiroyoshi

AU - Tanaka, Akihito

AU - Regazzoli, Damiano

AU - Mangieri, Antonio

AU - Montalto, Claudio

AU - Ancona, Marco B.

AU - Giannini, Francesco

AU - Chieffo, Alaide

AU - Montorfano, Matteo

AU - Monaco, Fabrizio

AU - Castiglioni, Alessandro

AU - Alfieri, Ottavio

AU - Colombo, Antonio

PY - 2016/1/21

Y1 - 2016/1/21

N2 - Balloon predilation is historically considered a requirement before performing transcatheter aortic valve implantation (TAVI). As the procedure has evolved, it has been questioned whether it is actually needed, but data are lacking on mid-term outcomes. The aim of this study was to evaluate the effect of balloon predilation before TAVI. A total of 517 patients who underwent transfemoral TAVI from November 2007 to October 2015 were analyzed. The devices implanted included the Medtronic CoreValve (n = 216), Medtronic Evolut R (n = 30), Edwards SAPIEN XT (n = 210), and Edwards SAPIEN 3 (n = 61). Patients were divided into 2 groups depending on whether pre-implantation balloon aortic valvuloplasty (pre-BAV) was performed (n = 326) or not (n = 191). Major adverse cardiac and cerebrovascular events (MACCE) were primarily evaluated. Propensity score matching was used to adjust for differences in baseline characteristics and potential confounders (n = 113 pairs). In the overall cohort, patients without pre-BAV had a significantly higher MACCE rate at 30 days, driven by a higher incidence of stroke (0.3% pre-BAV vs 3.7% no-pre-BAV, p

AB - Balloon predilation is historically considered a requirement before performing transcatheter aortic valve implantation (TAVI). As the procedure has evolved, it has been questioned whether it is actually needed, but data are lacking on mid-term outcomes. The aim of this study was to evaluate the effect of balloon predilation before TAVI. A total of 517 patients who underwent transfemoral TAVI from November 2007 to October 2015 were analyzed. The devices implanted included the Medtronic CoreValve (n = 216), Medtronic Evolut R (n = 30), Edwards SAPIEN XT (n = 210), and Edwards SAPIEN 3 (n = 61). Patients were divided into 2 groups depending on whether pre-implantation balloon aortic valvuloplasty (pre-BAV) was performed (n = 326) or not (n = 191). Major adverse cardiac and cerebrovascular events (MACCE) were primarily evaluated. Propensity score matching was used to adjust for differences in baseline characteristics and potential confounders (n = 113 pairs). In the overall cohort, patients without pre-BAV had a significantly higher MACCE rate at 30 days, driven by a higher incidence of stroke (0.3% pre-BAV vs 3.7% no-pre-BAV, p

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Usefulness of Predilation Before Transcatheter Aortic Valve Implantation

Abstract

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