Usefulness of Predilation Before Transcatheter Aortic Valve Implantation

Matteo Pagnesi, Richard J. Jabbour, Azeem Latib, Hiroyoshi Kawamoto, Akihito Tanaka, Damiano Regazzoli, Antonio Mangieri, Claudio Montalto, Marco B. Ancona, Francesco Giannini, Alaide Chieffo, Matteo Montorfano, Fabrizio Monaco, Alessandro Castiglioni, Ottavio Alfieri, Antonio Colombo

Research output: Contribution to journalArticlepeer-review


Balloon predilation is historically considered a requirement before performing transcatheter aortic valve implantation (TAVI). As the procedure has evolved, it has been questioned whether it is actually needed, but data are lacking on mid-term outcomes. The aim of this study was to evaluate the effect of balloon predilation before TAVI. A total of 517 patients who underwent transfemoral TAVI from November 2007 to October 2015 were analyzed. The devices implanted included the Medtronic CoreValve (n = 216), Medtronic Evolut R (n = 30), Edwards SAPIEN XT (n = 210), and Edwards SAPIEN 3 (n = 61). Patients were divided into 2 groups depending on whether pre-implantation balloon aortic valvuloplasty (pre-BAV) was performed (n = 326) or not (n = 191). Major adverse cardiac and cerebrovascular events (MACCE) were primarily evaluated. Propensity score matching was used to adjust for differences in baseline characteristics and potential confounders (n = 113 pairs). In the overall cohort, patients without pre-BAV had a significantly higher MACCE rate at 30 days, driven by a higher incidence of stroke (0.3% pre-BAV vs 3.7% no-pre-BAV, p

Original languageEnglish
JournalThe American Journal of Cardiology
Publication statusAccepted/In press - Jan 21 2016

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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