TY - JOUR
T1 - Usefulness of Stress Cardiac Single-Photon Emission Computed Tomographic Imaging Late After Percutaneous Coronary Intervention for Assessing Cardiac Events and Time to Such Events
AU - Acampa, Wanda
AU - Evangelista, Laura
AU - Petretta, Mario
AU - Liuzzi, Raffaele
AU - Cuocolo, Alberto
PY - 2007/8/1
Y1 - 2007/8/1
N2 - This study assessed the predictors and temporal characteristics of cardiac risk in patients undergoing stress single-photon emission computed tomography (SPECT) after percutaneous coronary intervention (PCI). Stress SPECT was performed in 346 patients 12 to 18 months after PCI. Cardiac death and myocardial infarction were considered events. Cox proportional hazards analysis was used to identify predictors of events and parametric survival analysis to predict time to events. During follow-up (31 ± 10 months), 17 events occurred (4.9% cumulative event rate). Prescan likelihood of ischemia and ischemia at SPECT were independent predictors of events (p 48 months in those with low prescan likelihood of ischemia and >20 months in those with intermediate to high prescan likelihood. Ischemia at SPECT was associated with higher probability of failure accelerating over time. In conclusion, clinical variables and stress SPECT performed 12 to 18 months after PCI are useful to characterize risk of cardiac events and its temporal variation. Parametric survival models seem useful to estimate predicted time to risk and levels of risk at specific intervals after PCI.
AB - This study assessed the predictors and temporal characteristics of cardiac risk in patients undergoing stress single-photon emission computed tomography (SPECT) after percutaneous coronary intervention (PCI). Stress SPECT was performed in 346 patients 12 to 18 months after PCI. Cardiac death and myocardial infarction were considered events. Cox proportional hazards analysis was used to identify predictors of events and parametric survival analysis to predict time to events. During follow-up (31 ± 10 months), 17 events occurred (4.9% cumulative event rate). Prescan likelihood of ischemia and ischemia at SPECT were independent predictors of events (p 48 months in those with low prescan likelihood of ischemia and >20 months in those with intermediate to high prescan likelihood. Ischemia at SPECT was associated with higher probability of failure accelerating over time. In conclusion, clinical variables and stress SPECT performed 12 to 18 months after PCI are useful to characterize risk of cardiac events and its temporal variation. Parametric survival models seem useful to estimate predicted time to risk and levels of risk at specific intervals after PCI.
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U2 - 10.1016/j.amjcard.2007.03.042
DO - 10.1016/j.amjcard.2007.03.042
M3 - Article
C2 - 17659924
AN - SCOPUS:34547127639
VL - 100
SP - 436
EP - 441
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 3
ER -