Our aim was to evaluate the usefulness of Fluid Attenuation Inversion Recovery sequences (Turbo-FLAIR) and of volumetric sequences in detecting signal intensity abnormalities and hippocampal cortical thickness changes in patients with drug-resistant temporal epilepsy. We studied 40 patients with drug-resistant temporal epilepsy with a 1.5 Tesla unit (NT 15 Philips Gyroscan). Conventional SE, Turbo SE, IR, Turbo-FLAIR, volumetric 3D sequences on coronal plane, PD, T2-weighted SE sequences on axial plane, T1- weighted SE on sagittal plane were performed. Signal intensity and volumetric computerized measurements were obtained using the SUN system. Differences in signal intensity values between the two hippocampal regions were found in 22 patients with Turbo-FLAIR sequences. In eight these patients no significant differences in computerized evaluation of signal intensity were detected with either conventional or Turbo-SE sequences. Volumetric analysis showed hippocampal cortex thinning in 12 out of 22 patients with hippocampal signal intensity abnormalities. Turbo-FLAIR provided the best sequences for the detection of signal intensity changes in the hippocampal region. Such changes are strongly suggestive of hippocampal sclerosis, especially when associated with cortical atrophy.
|Number of pages||4|
|Journal||Rivista di Neuroradiologia|
|Publication status||Published - 1998|
ASJC Scopus subject areas
- Clinical Neurology
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology