Uterine changes during Tamoxifen therapy

S. Rullo, T. Tagliaferri, F. Bandiera, C. Fiorelli, A. Felici, M. G. Piccioni, M. L. Framarino Dei Malatesta

Research output: Contribution to journalArticle

Abstract

Tamoxifen used for adjuvant therapy in breast cancer, has a complex and unclear action on endometrium and myometrium. Many authors demonstrated endometrial proliferous changes in peri and post-menopausal women. Our study shows the development of myomas in three patients without uterine pathology before tamoxifen therapy, and the increase of a polip and a myoma after tamoxifen therapy. Moreover, we observed the development of a myoma in a patient after one year tamoxifen in association with LH-RH analogue therapy. It is necessary to continue our study with a larger number of patients to asses the hyperplasic effect of tamoxifen.

Original languageEnglish
Pages (from-to)116-119
Number of pages4
JournalClinical and Experimental Obstetrics and Gynecology
Volume20
Issue number2
Publication statusPublished - 1993

Fingerprint

Tamoxifen
Myoma
Therapeutics
Myometrium
Equidae
Endometrium
Gonadotropin-Releasing Hormone
Pathology
Breast Neoplasms

Keywords

  • hysteroscopie
  • tamoxifen
  • uterine changes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Rullo, S., Tagliaferri, T., Bandiera, F., Fiorelli, C., Felici, A., Piccioni, M. G., & Framarino Dei Malatesta, M. L. (1993). Uterine changes during Tamoxifen therapy. Clinical and Experimental Obstetrics and Gynecology, 20(2), 116-119.

Uterine changes during Tamoxifen therapy. / Rullo, S.; Tagliaferri, T.; Bandiera, F.; Fiorelli, C.; Felici, A.; Piccioni, M. G.; Framarino Dei Malatesta, M. L.

In: Clinical and Experimental Obstetrics and Gynecology, Vol. 20, No. 2, 1993, p. 116-119.

Research output: Contribution to journalArticle

Rullo, S, Tagliaferri, T, Bandiera, F, Fiorelli, C, Felici, A, Piccioni, MG & Framarino Dei Malatesta, ML 1993, 'Uterine changes during Tamoxifen therapy', Clinical and Experimental Obstetrics and Gynecology, vol. 20, no. 2, pp. 116-119.
Rullo S, Tagliaferri T, Bandiera F, Fiorelli C, Felici A, Piccioni MG et al. Uterine changes during Tamoxifen therapy. Clinical and Experimental Obstetrics and Gynecology. 1993;20(2):116-119.
Rullo, S. ; Tagliaferri, T. ; Bandiera, F. ; Fiorelli, C. ; Felici, A. ; Piccioni, M. G. ; Framarino Dei Malatesta, M. L. / Uterine changes during Tamoxifen therapy. In: Clinical and Experimental Obstetrics and Gynecology. 1993 ; Vol. 20, No. 2. pp. 116-119.
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