Uterine sarcomas: A clinicopathologic study

S. Chiara, G. Foglia, F. Odicino, A. Graziani, P. F. Conte, N. Ragni, E. Fulcheri, G. Pescetto

Research output: Contribution to journalArticlepeer-review

Abstract

A series of 48 cases with initial diagnosis of uterine sarcoma was reviewed to evaluate the validity of histologic criteria. The influence of pathologic and clinical prognostic factors and treatment modalities were examined. The 32 patients included in this retrospective study after pathologic review had 5-year overall survival rate of 13.1%. Surgical pathological staging was demonstrated to be a significant prognostic factor, since patients with FIGO stage I-II disease had 33.5% actuarial survival rate whereas no patient with stage III-IV disease was alive at 37 months. Histological type, age and menopausal status did not significantly influence survival. Presence of heterologous elements and lymphovascular invasion were associated with a poor prognosis in the subgroup of patients with mixed mesodermal tumors. Median survival for patients receiving adjuvant treatment was 25 months compared to 19 months for those undergoing no adjuvant therapy.

Original languageEnglish
Pages (from-to)428-433
Number of pages6
JournalOncology
Volume45
Issue number6
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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