Utilitá di un follow-up endoscopico nei pazienti resecati per cancro del colon retto

Translated title of the contribution: Utility of endoscopic follow-up after radical surgery for colorectal cancer

V. Stigliano, P. Fracasso, A. Grassi, R. Lapenta, F. Citarda, G. Tomaselli, D. Giannarelli, V. Casale

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Patients resected for colorectal cancer are at incresed risk for an anastomotic recurrence, for adenomatous polyps and for a metachronous cancer. A regular colonoscopic surveillance in these patients is justified for early detection and potential resection of anastomotic recurrences, new primary cancer and adenomatous polyps. Patients and Methods: 322 patients were observed and resected for colorectal cancer between 1970 and 1988, with complete staging agreed to be included in a follow-up program (median follow-up: 105 months). To December 1993 all the patients were submitted to colonoscopy once yearly for the first 5 years and then every 2 years. Results: Anastomotic recurrence was observed in 22 of the 253 patients who underwent resection for rectal or sigmoid adenocarcinoma (8.7%). Sixteen of these patients were submitted to a second curative resection with a median survival of 35 months; the median survival was 6 months in the 6 patients who could not undergo this operation (p=0.0018). Metachronous adenomas of the residual colon were found in 24 patients (7,4%) and metachronous cancers in 5 (1,5%) at Stage A, according to Dukes' classification. Conclusions: In patients resected for rectal or sigmoid carcinoma, a sigmoidoscopy should be performed every 6 months for the first 2 years for the early detection of anastomotic recurrences. In all cases, a colonoscopy should be performed every 5 years after surgery to detect metachronous lesions at early stage. Before surgery, a "clean colon" should always be established to detect possible synchronous lesions.

Translated title of the contributionUtility of endoscopic follow-up after radical surgery for colorectal cancer
Original languageItalian
Pages (from-to)323-326
Number of pages4
JournalClinica Terapeutica
Volume153
Issue number5
Publication statusPublished - Sep 2002

ASJC Scopus subject areas

  • Medicine(all)

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