Abstract
Purpose: Patients resected for colorectal cancer are at incresed risk for an anastomotic recurrence, for adenomatous polyps and for a metachronous cancer. A regular colonoscopic surveillance in these patients is justified for early detection and potential resection of anastomotic recurrences, new primary cancer and adenomatous polyps. Patients and Methods: 322 patients were observed and resected for colorectal cancer between 1970 and 1988, with complete staging agreed to be included in a follow-up program (median follow-up: 105 months). To December 1993 all the patients were submitted to colonoscopy once yearly for the first 5 years and then every 2 years. Results: Anastomotic recurrence was observed in 22 of the 253 patients who underwent resection for rectal or sigmoid adenocarcinoma (8.7%). Sixteen of these patients were submitted to a second curative resection with a median survival of 35 months; the median survival was 6 months in the 6 patients who could not undergo this operation (p=0.0018). Metachronous adenomas of the residual colon were found in 24 patients (7,4%) and metachronous cancers in 5 (1,5%) at Stage A, according to Dukes' classification. Conclusions: In patients resected for rectal or sigmoid carcinoma, a sigmoidoscopy should be performed every 6 months for the first 2 years for the early detection of anastomotic recurrences. In all cases, a colonoscopy should be performed every 5 years after surgery to detect metachronous lesions at early stage. Before surgery, a "clean colon" should always be established to detect possible synchronous lesions.
| Original language | Italian |
|---|---|
| Pages (from-to) | 323-326 |
| Number of pages | 4 |
| Journal | Clinica Terapeutica |
| Volume | 153 |
| Issue number | 5 |
| Publication status | Published - Sep 2002 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Utilitá di un follow-up endoscopico nei pazienti resecati per cancro del colon retto. / Stigliano, V.; Fracasso, P.; Grassi, A.; Lapenta, R.; Citarda, F.; Tomaselli, G.; Giannarelli, D.; Casale, V.
In: Clinica Terapeutica, Vol. 153, No. 5, 09.2002, p. 323-326.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Utilitá di un follow-up endoscopico nei pazienti resecati per cancro del colon retto
AU - Stigliano, V.
AU - Fracasso, P.
AU - Grassi, A.
AU - Lapenta, R.
AU - Citarda, F.
AU - Tomaselli, G.
AU - Giannarelli, D.
AU - Casale, V.
PY - 2002/9
Y1 - 2002/9
N2 - Purpose: Patients resected for colorectal cancer are at incresed risk for an anastomotic recurrence, for adenomatous polyps and for a metachronous cancer. A regular colonoscopic surveillance in these patients is justified for early detection and potential resection of anastomotic recurrences, new primary cancer and adenomatous polyps. Patients and Methods: 322 patients were observed and resected for colorectal cancer between 1970 and 1988, with complete staging agreed to be included in a follow-up program (median follow-up: 105 months). To December 1993 all the patients were submitted to colonoscopy once yearly for the first 5 years and then every 2 years. Results: Anastomotic recurrence was observed in 22 of the 253 patients who underwent resection for rectal or sigmoid adenocarcinoma (8.7%). Sixteen of these patients were submitted to a second curative resection with a median survival of 35 months; the median survival was 6 months in the 6 patients who could not undergo this operation (p=0.0018). Metachronous adenomas of the residual colon were found in 24 patients (7,4%) and metachronous cancers in 5 (1,5%) at Stage A, according to Dukes' classification. Conclusions: In patients resected for rectal or sigmoid carcinoma, a sigmoidoscopy should be performed every 6 months for the first 2 years for the early detection of anastomotic recurrences. In all cases, a colonoscopy should be performed every 5 years after surgery to detect metachronous lesions at early stage. Before surgery, a "clean colon" should always be established to detect possible synchronous lesions.
AB - Purpose: Patients resected for colorectal cancer are at incresed risk for an anastomotic recurrence, for adenomatous polyps and for a metachronous cancer. A regular colonoscopic surveillance in these patients is justified for early detection and potential resection of anastomotic recurrences, new primary cancer and adenomatous polyps. Patients and Methods: 322 patients were observed and resected for colorectal cancer between 1970 and 1988, with complete staging agreed to be included in a follow-up program (median follow-up: 105 months). To December 1993 all the patients were submitted to colonoscopy once yearly for the first 5 years and then every 2 years. Results: Anastomotic recurrence was observed in 22 of the 253 patients who underwent resection for rectal or sigmoid adenocarcinoma (8.7%). Sixteen of these patients were submitted to a second curative resection with a median survival of 35 months; the median survival was 6 months in the 6 patients who could not undergo this operation (p=0.0018). Metachronous adenomas of the residual colon were found in 24 patients (7,4%) and metachronous cancers in 5 (1,5%) at Stage A, according to Dukes' classification. Conclusions: In patients resected for rectal or sigmoid carcinoma, a sigmoidoscopy should be performed every 6 months for the first 2 years for the early detection of anastomotic recurrences. In all cases, a colonoscopy should be performed every 5 years after surgery to detect metachronous lesions at early stage. Before surgery, a "clean colon" should always be established to detect possible synchronous lesions.
KW - Colorectal cancer
KW - Follow-up
KW - Methachronous neoplasm
UR - http://www.scopus.com/inward/record.url?scp=0036708824&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036708824&partnerID=8YFLogxK
M3 - Articolo
C2 - 12510416
AN - SCOPUS:0036708824
VL - 153
SP - 323
EP - 326
JO - Clinica Terapeutica
JF - Clinica Terapeutica
SN - 0009-9074
IS - 5
ER -