Utility of serological screening for measles, mumps and rubella in immunocompromised patients

L. Sticchi, M. Astengo, I. G. Iavarone, G. Icardi

Research output: Contribution to journalArticle

Abstract

Marchi et al. in their article (Measles in pregnancy: a threat for Italian women? Hum Vaccin Immunother. 2019 Jun 20:1–3) observed that 96.9% of pregnant women were positive for anti-measles IgG (with a higher risk of contracting measles in those aged 19–29 years) emphasizing the importance of serological screening before pregnancy. We evaluated seroprotection/seropositivity rates to Measles, Mumps and Rubella in 324 adults with an acquired immune-deficiency needing an immunization program. We found that younger patients (20–29 years) had a seroprevalence below 85%. Overall, a relevant proportion (21.6%, 54/250) of patients was susceptible to at least one infection needing immunization. Our results confirm the usefulness of proper strategies for identifying individuals susceptible to vaccine-preventable infections and protecting them through vaccination.

Original languageEnglish
JournalHuman Vaccines and Immunotherapeutics
DOIs
Publication statusAccepted/In press - Jan 1 2019

Fingerprint

Mumps
Rubella
Measles
Immunocompromised Host
Pregnancy
Immunization Programs
Seroepidemiologic Studies
Infection
Pregnant Women
Immunization
Vaccination
Vaccines

Keywords

  • Italy
  • Measles
  • mumps
  • rubella
  • vaccination

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pharmacology

Cite this

Utility of serological screening for measles, mumps and rubella in immunocompromised patients. / Sticchi, L.; Astengo, M.; Iavarone, I. G.; Icardi, G.

In: Human Vaccines and Immunotherapeutics, 01.01.2019.

Research output: Contribution to journalArticle

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