Vaccine strategies for infectious diseases

M. Clerici, S. Piconi, D. Trabattoni

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Infectious diseases are the major cause of death worldwide; in developing countries such diseases are responsible for nearly half the burden of premature death and disability. Therefore, the need for the development of new vaccine strategies aimed at preventing or limiting disease is extremely urgent. Important successes have been achieved against some infectious diseases that were once endemic or, even, epidemic (e.g., polio, smallpox, diptheria). Advances in our knowledge of the pathogenesis and immune correlates of protections are needed to develop novel vaccinal approaches to diseases such as hepatitis C, AIDS and malaria. In this review we will analyse the biological problems associated with the prevention of development and/or improvement of vaccine strategies for infectious diseases, focusing on the difficulties facing the creation of new effective vaccines for HIV infection and malaria.

Original languageEnglish
Pages (from-to)95-106
Number of pages12
JournalExpert Opinion on Investigational Drugs
Volume8
Issue number2
DOIs
Publication statusPublished - 1999

Fingerprint

Communicable Diseases
Vaccines
Malaria Vaccines
Premature Mortality
Smallpox
Poliomyelitis
Hepatitis C
Developing Countries
Malaria
HIV Infections
Cause of Death
Acquired Immunodeficiency Syndrome

Keywords

  • HIV
  • Immunology
  • Malaria
  • Vaccines

ASJC Scopus subject areas

  • Pharmacology

Cite this

Vaccine strategies for infectious diseases. / Clerici, M.; Piconi, S.; Trabattoni, D.

In: Expert Opinion on Investigational Drugs, Vol. 8, No. 2, 1999, p. 95-106.

Research output: Contribution to journalArticle

Clerici, M. ; Piconi, S. ; Trabattoni, D. / Vaccine strategies for infectious diseases. In: Expert Opinion on Investigational Drugs. 1999 ; Vol. 8, No. 2. pp. 95-106.
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