La neurostimolazione vagale in Neurologia e Psichiatria

Translated title of the contribution: Vagus nerve stimulation in Neurology and Psychiatry

Gennaro Bussone, Cesare Peccarisi, Alberto Proietti Cecchini, Angelo Franzini

Research output: Contribution to journalArticlepeer-review


Introduction: Recent progress in biotechnology and neuroimaging has enlarged the possibilities for applying neurostimulation procedures to treat common neuropsychiatric conditions and chronic pain disorders. These conditions are refractory to pharmacological and other conventional treatments, to variable degrees, and are associated with a heavy social and economic burden. Refinements in neuroanatomical targeting have enlarged the clinical indications for these neurostimulation treatments, and increased the need to identify robust patient selection criteria. Neurostimulation is a relatively low invasivity procedure, and may be safer than conventional treatments, mainly because it is fully reversible, but also because it is highly flexible, offering a wide range of modulation (amplitude, duration, frequency) and stimulation (unipolar/bipolar, continuous/cycling, unilateral/bilateral) modes. There are various types of neurostimulation technique which promise great therapeutic potential now extending from Neurology to Psychiatry that is still only partly explored. The present paper reviews the clinical applications of these techniques, presenting main results and discussing limitations, with particular regard to newest applications of vagal nerve stimulation.

Translated title of the contributionVagus nerve stimulation in Neurology and Psychiatry
Original languageItalian
Pages (from-to)146-157
Number of pages12
JournalQuaderni Italiani di Psichiatria
Issue number4
Publication statusPublished - Dec 2010

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Phychiatric Mental Health


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