Vagus nerve stimulation in refractory epilepsy: New indications and outcome assessment

Carlo Efisio Marras, Valentina Chiesa, Alessandro De Benedictis, Angelo Franzini, Michele Rizzi, Flavio Villani, Francesca Ragona, Laura Tassi, Aglaia Vignoli, Elena Freri, Nicola Specchio, Giovanni Broggi, Marina Casazza, Maria Paola Canevini

Research output: Contribution to journalArticlepeer-review


Although vagus nerve stimulation (VNS) is an effective alternative option for patients with refractory epilepsy unsuitable for conventional resective surgery, predictors of a better control of seizure frequency and severity are still unavailable. This prospective study reports on 39 patients, including 4 children affected by epilepsia partialis continua (EPC), who underwent VNS for refractory epilepsy. The overall seizure frequency outcome was classified into three groups according to reduction rate: ≥. 75%, ≥. 50%, and

Original languageEnglish
Pages (from-to)374-378
Number of pages5
JournalEpilepsy and Behavior
Issue number3
Publication statusPublished - Sep 2013


  • Palliative surgery
  • Refractory epilepsy
  • Vagus nerve stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology


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