Validation of a home environment test battery for supporting assessments in advanced Parkinson's disease

Jerker Westin, Mauro Schiavella, Mevludin Memedi, Dag Nyholm, Mark Dougherty, Angelo Antonini

Research output: Contribution to journalArticle

Abstract

Test sequences in a test battery for Parkinson's disease patients, consisting of self-assessments and motor tests, were carried out repeatedly in a telemedicine setting, during week-long test periods and results were summarized in an 'overall score'. 35 patients in stable and fluctuating conditions (15 age- and gender-matched pairs) used the test battery for 1 week, and were then assessed with UPDRS and PDQ-39. This procedure was repeated 1 week later, without treatment changes. Reliability was assessed by intraclass correlation coefficients and Cronbach's alpha. Convergent validity was assessed by Spearman rank correlations and known-groups' validity, by the Mann-Whitney test. According to anonymous usability questionnaires, the patients could easily complete the tasks. Median compliance (93%) and test-retest reliability (0.88) were good. The correlations between overall score and total UPDRS (-0.64) and PDQ-39 (-0.72) were adequate. Median overall score was 18% better in the stable compared to the fluctuating group (p = 0.0014).

Original languageEnglish
Pages (from-to)831-838
Number of pages8
JournalNeurological Sciences
Volume33
Issue number4
DOIs
Publication statusPublished - Aug 2012

Keywords

  • Motor fluctuations
  • Motor tests
  • Parkinson's disease
  • Self-assessment
  • Telemedicine
  • Validity

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology

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