Validation of the Italian version of the Coma Recovery Scale-Revised (CRS-R)

Primary objective: To validate the Italian version of the Coma Recovery Scale-Revised (CRS-R). Methods: Two observers applied the Italian version of the CRS-R to selected patients. On day 1, observer A and B independently scored each patient; the comparison of their observations was used to evaluate inter-observer agreement. On day 2, observer A completed a second evaluation and the comparison of this observation with that obtained on day 1 by the same observer was used to evaluate test-re-test agreement. For each evaluation, also diagnostic impression (vegetative state/minimally conscious state) was reported. Results: Thirty-eight patients were evaluated (mean age±SD, 58.9±13.8 years). Inter-observer (ρ=0.81; p