Abstract
This article reviews relevant pharmacologic and clinical information gathered for valproate since it was introduced into clinical practice 37 years ago and the application of this information for the treatment of childhood epilepsy. Valproate is available for oral and parenteral use. Oral forms are almost completely bioavailable but the rate of absorption varies between formulations. The Chrono® tablet formulation has not been adapted for children aged
Original language | English |
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Pages (from-to) | 113-129 |
Number of pages | 17 |
Journal | Pediatric Drugs |
Volume | 8 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2006 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Pharmacology