Abstract
Background and aims. The recreational use of cocaine is associated with cardiovascular pathologies, such as ischemic cardiopathy, myocarditis and cardiomyopathies, owing to the increased catecholamine stimulus, a propensity to coronary spasm, increased coagulative activity and inflammatory and degenerative phenomena of myocardiac cells. Early alterations of the diastolic phase may be visualised by evaluating the diastolic Doppler pattern of left ventricular filling. Methods. For this purpose the authors compared blood pressure, heart rate, heart mass, protodiastolic (E wave) and telediastolic (A wave) filling rate and their ratio (E/A) on the Doppler mitral diastolic profile in a group of 10 patients addicted to the recreational use of cocaine (mean age 33±7) with those of 10 normal subjects (mean age 34±2). Results. Patients using cocaine presented mean systolic arterial blood pressures of 130±12 versus 127±8 in control subjects (p=ns); mean heart rate was statistically significant with 98±14 versus 76±12 in controls (p
| Original language | Italian |
|---|---|
| Pages (from-to) | 489-493 |
| Number of pages | 5 |
| Journal | Minerva Cardioangiologica |
| Volume | 45 |
| Issue number | 10 |
| Publication status | Published - Oct 1997 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Valutazione del rilasciamento ventricolare sinistro nei pazienti dediti all'uso voluttuario di cocaina. / Mondillo, S.; Agricola, E.; D'Aprile, N.; Nicoletti, A.; Palazzuoli, V.
In: Minerva Cardioangiologica, Vol. 45, No. 10, 10.1997, p. 489-493.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Valutazione del rilasciamento ventricolare sinistro nei pazienti dediti all'uso voluttuario di cocaina
AU - Mondillo, S.
AU - Agricola, E.
AU - D'Aprile, N.
AU - Nicoletti, A.
AU - Palazzuoli, V.
PY - 1997/10
Y1 - 1997/10
N2 - Background and aims. The recreational use of cocaine is associated with cardiovascular pathologies, such as ischemic cardiopathy, myocarditis and cardiomyopathies, owing to the increased catecholamine stimulus, a propensity to coronary spasm, increased coagulative activity and inflammatory and degenerative phenomena of myocardiac cells. Early alterations of the diastolic phase may be visualised by evaluating the diastolic Doppler pattern of left ventricular filling. Methods. For this purpose the authors compared blood pressure, heart rate, heart mass, protodiastolic (E wave) and telediastolic (A wave) filling rate and their ratio (E/A) on the Doppler mitral diastolic profile in a group of 10 patients addicted to the recreational use of cocaine (mean age 33±7) with those of 10 normal subjects (mean age 34±2). Results. Patients using cocaine presented mean systolic arterial blood pressures of 130±12 versus 127±8 in control subjects (p=ns); mean heart rate was statistically significant with 98±14 versus 76±12 in controls (p
AB - Background and aims. The recreational use of cocaine is associated with cardiovascular pathologies, such as ischemic cardiopathy, myocarditis and cardiomyopathies, owing to the increased catecholamine stimulus, a propensity to coronary spasm, increased coagulative activity and inflammatory and degenerative phenomena of myocardiac cells. Early alterations of the diastolic phase may be visualised by evaluating the diastolic Doppler pattern of left ventricular filling. Methods. For this purpose the authors compared blood pressure, heart rate, heart mass, protodiastolic (E wave) and telediastolic (A wave) filling rate and their ratio (E/A) on the Doppler mitral diastolic profile in a group of 10 patients addicted to the recreational use of cocaine (mean age 33±7) with those of 10 normal subjects (mean age 34±2). Results. Patients using cocaine presented mean systolic arterial blood pressures of 130±12 versus 127±8 in control subjects (p=ns); mean heart rate was statistically significant with 98±14 versus 76±12 in controls (p
KW - Cocaine Adverse effects
KW - Diastole
KW - Doppler
KW - Echocardiography
UR - http://www.scopus.com/inward/record.url?scp=0031422680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031422680&partnerID=8YFLogxK
M3 - Articolo
C2 - 9489318
AN - SCOPUS:0031422680
VL - 45
SP - 489
EP - 493
JO - Minerva Cardioangiologica
JF - Minerva Cardioangiologica
SN - 0026-4725
IS - 10
ER -