Valutazione del rilasciamento ventricolare sinistro nei pazienti dediti all'uso voluttuario di cocaina

Translated title of the contribution: Valuation of diastolic function in patients addicted to recreational cocaine use

S. Mondillo, E. Agricola, N. D'Aprile, A. Nicoletti, V. Palazzuoli

Research output: Contribution to journalArticle

Abstract

Background and aims. The recreational use of cocaine is associated with cardiovascular pathologies, such as ischemic cardiopathy, myocarditis and cardiomyopathies, owing to the increased catecholamine stimulus, a propensity to coronary spasm, increased coagulative activity and inflammatory and degenerative phenomena of myocardiac cells. Early alterations of the diastolic phase may be visualised by evaluating the diastolic Doppler pattern of left ventricular filling. Methods. For this purpose the authors compared blood pressure, heart rate, heart mass, protodiastolic (E wave) and telediastolic (A wave) filling rate and their ratio (E/A) on the Doppler mitral diastolic profile in a group of 10 patients addicted to the recreational use of cocaine (mean age 33±7) with those of 10 normal subjects (mean age 34±2). Results. Patients using cocaine presented mean systolic arterial blood pressures of 130±12 versus 127±8 in control subjects (p=ns); mean heart rate was statistically significant with 98±14 versus 76±12 in controls (p

Translated title of the contributionValuation of diastolic function in patients addicted to recreational cocaine use
Original languageItalian
Pages (from-to)489-493
Number of pages5
JournalMinerva Cardioangiologica
Volume45
Issue number10
Publication statusPublished - Oct 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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