Variation in nocturnal urinary excretion of melatonin in a group of patients older than 55 years suffering from urogenital tract disorders.

G. Taverna, A. Trinchieri, A. Mandressi, A. Del Nero, B. Mangiarotti, D. Antonelli, S. Chisena, E. Pisani

Research output: Contribution to journalArticle

Abstract

Melatonin (MLT) is directly or indirectly related to cell growth (both of normal and neoplastic cells), to the immune system stimulation and to the endocrine system modulation. This controlled study was carried out to evaluate urinary excretion of MLT in patients suffering from urogenital tract disorders. Eighty-one patients affected by urogenital disorders were divided in two groups (neoplastic and non-neoplastic) and urinary excretion of MLT was evaluated. Mean diurnal (from 8 a.m. to p.m.) urinary excretion of MLT was 4.97 + 6.08 pg/12 h in non-oncologic patients and 4.82 + 6.21 pg/12 h in oncologic patients (p = 0.50). Mean nocturnal (from 8 p.m. at 8 a.m.) urinary excretion of MLT was 11.97 + 9.34 pg/12 h in non-oncologic patients while in oncologic patients it was 7.86 + 8.95 pg/12 h. Statistically significant variation in nocturnal urinary excretion of melatonin was observed in oncologic patients (p = 0.022) versus non oncologic patients.

Original languageEnglish
Pages (from-to)293-297
Number of pages5
JournalArchivio Italiano di Urologia e Andrologia
Volume69
Issue number5
Publication statusPublished - Dec 1997

ASJC Scopus subject areas

  • Nephrology
  • Urology

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    Taverna, G., Trinchieri, A., Mandressi, A., Del Nero, A., Mangiarotti, B., Antonelli, D., Chisena, S., & Pisani, E. (1997). Variation in nocturnal urinary excretion of melatonin in a group of patients older than 55 years suffering from urogenital tract disorders. Archivio Italiano di Urologia e Andrologia, 69(5), 293-297.