Variation in preoperative antithrombotic strategy, severe bleeding, and use of blood products in coronary artery bypass grafting

Fausto Biancari, Giovanni Mariscalco, Riccardo Gherli, Daniel Reichart, Francesco Onorati, Giuseppe Faggian, Ilaria Franzese, Giuseppe Santarpino, Theodor Fischlein, Antonino S Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Vito G Ruggieri, Karl Bounader, Andrea Perrotti, Stefano RosatoPaola D'Errigo, Vito D'Andrea, Marisa De Feo, Tuomas Tauriainen, Giuseppe Gatti, Magnus Dalén

Research output: Contribution to journalArticle

Abstract

Aims: No data exists on inter-institutional differences in terms of adherence to international guidelines regarding the discontinuation of antithrombotics and rates of severe bleeding in coronary artery bypass grafting (CABG).Methods and results: This is an analysis of 7118 patients from the prospective multicentre European CABG (E-CABG) registry who underwent isolated CABG in 15 European centres. Preoperative pause of P2Y12 receptor antagonists shorter than that suggested by the 2017 ESC guidelines (overall 11.6%) ranged from 0.7% to 24.8% between centres (adjusted P 
Original languageEnglish
Pages (from-to)246-257
Number of pages12
JournalEuropean heart journal. Quality of care & clinical outcomes
Volume4
Issue number4
DOIs
Publication statusPublished - Oct 1 2018

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Coronary Artery Bypass
Hemorrhage
Purinergic P2Y Receptor Antagonists
Guidelines
Registries

Keywords

  • antithrombotic
  • Bleeding
  • Blood product
  • coronary artery
  • Coronary Artery Disease/surgery

Cite this

Variation in preoperative antithrombotic strategy, severe bleeding, and use of blood products in coronary artery bypass grafting. / Biancari, Fausto; Mariscalco, Giovanni; Gherli, Riccardo; Reichart, Daniel; Onorati, Francesco; Faggian, Giuseppe; Franzese, Ilaria; Santarpino, Giuseppe; Fischlein, Theodor; Rubino, Antonino S; Maselli, Daniele; Nardella, Saverio; Salsano, Antonio; Nicolini, Francesco; Zanobini, Marco; Saccocci, Matteo; Ruggieri, Vito G; Bounader, Karl; Perrotti, Andrea; Rosato, Stefano; D'Errigo, Paola; D'Andrea, Vito; De Feo, Marisa; Tauriainen, Tuomas; Gatti, Giuseppe; Dalén, Magnus.

In: European heart journal. Quality of care & clinical outcomes, Vol. 4, No. 4, 01.10.2018, p. 246-257.

Research output: Contribution to journalArticle

Biancari, F, Mariscalco, G, Gherli, R, Reichart, D, Onorati, F, Faggian, G, Franzese, I, Santarpino, G, Fischlein, T, Rubino, AS, Maselli, D, Nardella, S, Salsano, A, Nicolini, F, Zanobini, M, Saccocci, M, Ruggieri, VG, Bounader, K, Perrotti, A, Rosato, S, D'Errigo, P, D'Andrea, V, De Feo, M, Tauriainen, T, Gatti, G & Dalén, M 2018, 'Variation in preoperative antithrombotic strategy, severe bleeding, and use of blood products in coronary artery bypass grafting', European heart journal. Quality of care & clinical outcomes, vol. 4, no. 4, pp. 246-257. https://doi.org/10.1093/ehjqcco/qcy027
Biancari, Fausto ; Mariscalco, Giovanni ; Gherli, Riccardo ; Reichart, Daniel ; Onorati, Francesco ; Faggian, Giuseppe ; Franzese, Ilaria ; Santarpino, Giuseppe ; Fischlein, Theodor ; Rubino, Antonino S ; Maselli, Daniele ; Nardella, Saverio ; Salsano, Antonio ; Nicolini, Francesco ; Zanobini, Marco ; Saccocci, Matteo ; Ruggieri, Vito G ; Bounader, Karl ; Perrotti, Andrea ; Rosato, Stefano ; D'Errigo, Paola ; D'Andrea, Vito ; De Feo, Marisa ; Tauriainen, Tuomas ; Gatti, Giuseppe ; Dalén, Magnus. / Variation in preoperative antithrombotic strategy, severe bleeding, and use of blood products in coronary artery bypass grafting. In: European heart journal. Quality of care & clinical outcomes. 2018 ; Vol. 4, No. 4. pp. 246-257.
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AU - Biancari, Fausto

AU - Mariscalco, Giovanni

AU - Gherli, Riccardo

AU - Reichart, Daniel

AU - Onorati, Francesco

AU - Faggian, Giuseppe

AU - Franzese, Ilaria

AU - Santarpino, Giuseppe

AU - Fischlein, Theodor

AU - Rubino, Antonino S

AU - Maselli, Daniele

AU - Nardella, Saverio

AU - Salsano, Antonio

AU - Nicolini, Francesco

AU - Zanobini, Marco

AU - Saccocci, Matteo

AU - Ruggieri, Vito G

AU - Bounader, Karl

AU - Perrotti, Andrea

AU - Rosato, Stefano

AU - D'Errigo, Paola

AU - D'Andrea, Vito

AU - De Feo, Marisa

AU - Tauriainen, Tuomas

AU - Gatti, Giuseppe

AU - Dalén, Magnus

PY - 2018/10/1

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KW - Bleeding

KW - Blood product

KW - coronary artery

KW - Coronary Artery Disease/surgery

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