Variation in the classification of polyneuropathies among European physicians

H. Tankisi, B. Johnsen, A. Fuglsang-Frederiksen, M. De Carvalho, P. R W Fawcett, A. Labarre-Vila, R. Liguori, W. Nix, M. Olsen, I. Schofield

Research output: Contribution to journalArticlepeer-review


Objective: Considerable debate still exists regarding the classification of polyneuropathies (PNPs) into predominantly demyelinating, predominantly axonal loss, mixed or unclassified. This study was designed to determine the variation among physicians in the classification of PNPs by using the European Standardized Telematic tool to Evaluate Electromyography knowledge-based systems and Methods (ESTEEM) multicenter database. Methods: Seven physicians from 6 laboratories in Europe sent a total of 156 prospectively collected cases of PNP with electromyography (EMG) data including diagnosis (examination diagnosis) to the database. Each physician interpreted the electrophysiological data from all cases (interpretation diagnosis) and a final diagnosis was given at the consensus meetings of the group (consensus diagnosis). Results: Comparison of each physician's examination diagnosis with his/her interpretation diagnosis, i.e. intra-physician variation, showed a change towards less classified PNPs (P

Original languageEnglish
Pages (from-to)496-503
Number of pages8
JournalClinical Neurophysiology
Issue number3
Publication statusPublished - Mar 1 2003


  • Electromyography
  • Multicenter electromyography database
  • Nerve conduction
  • Polyneuropathy
  • Variation in polyneuropathy classification

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)


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