Variations in survival for invasive cervical cancer among European women, 1978-89

G. Gatta, R. Capocaccia, T. Hakulinen, L. Sant, A. Verdecchia, G. De Angelis, A. Micheli, F. Berrino, W. Oberaigner, H. Storm, T. Aareleid, J. Mace-Lesee'h, D. Pottier, H. Faivre, P. M. Carli, G. Chaplain, P. Arveux, J. Esteve, F. Menegoz, N. RaverdyH. Ziegler, L. Tryggvadottir, H. Tulinius, E. Conti, M. Vercelli, M. Federico, L. Mangone, M. Ponz de Leon, V. De Lisi, R. Zanetti, L. Gafa, R. Tumino, F. Falcini, A. Barchielli, F. Valente, H. Pawlega, J. Rachtan, M. Bielska-Lasota, Z. Wronkowski, A. Obstnikova, I. Plesko, V. Pompe-Kirn, I. Izarzugaza, P. Viladiu, C. Martinez-Garcia, I. Garau, E. Ardanaz, C. Moreno, J. Galceran, T. Moller, J. Torhurst, C. Bouchardy, L. Raymond, J. W W Coebergh, R. Damius, A. Gould, R. J. Black, T. W. Davies, D. Stockton, M. P. Coleman, E. M I Williams, J. Littler, D. Forman, M. J. Quinn, M. Roche, J. Smith, J. Bell, G. Lawrence

Research output: Contribution to journalArticle

Abstract

Objectives: To analyze cervical cancer survival trends in 10 European countries using models that estimate the proportion of cured patients (having the same life expectancy as the general population) and the survival of fatal cases (who die from cervical cancel). Methods: We considered 40.906 cases diagnosed over 12 years (1978-89) collected from cancer registries participating in EUROCARE. Results: From 1978 to 1989, 5-year relative survival in Europe improved (60%→63%). The proportion of cured patients increased slightly but significantly (53%→55%, p = 0.05). For countries with poorer survival at the end of the 1970s the proportion of cured patients increased faster than average, particularly evident in England (49%→56%) and Scotland (44%→53%). By contrast, in Finland, Sweden and Germany with organized screening, 5-year survival and cure rate did not improve, but incidence declined to very low levels. Conclusions: Cervical screening can explain the trends in cervical cancer survival, this identifies premalignant lesions, reduces incidence and selectively prevents less aggressive cancers. The decreased proportion of the latter means that survival does not improve in countries with low incidence of cervical cancer. The increased proportion of cured patients with time shows that survival improvement was not due simply to earlier diagnosis with no patient advantage.

Original languageEnglish
Pages (from-to)575-581
Number of pages7
JournalCancer Causes and Control
Volume10
Issue number6
DOIs
Publication statusPublished - 1999

Fingerprint

Uterine Cervical Neoplasms
Survival
Incidence
Scotland
Finland
Life Expectancy
Sweden
England
Germany
Registries
Early Diagnosis
Neoplasms
Survival Rate
Population

Keywords

  • Cervical cancer
  • Cured patients
  • Europe
  • Population-based cancer registries
  • Relative survival

ASJC Scopus subject areas

  • Oncology
  • Epidemiology
  • Cancer Research

Cite this

Gatta, G., Capocaccia, R., Hakulinen, T., Sant, L., Verdecchia, A., De Angelis, G., ... Lawrence, G. (1999). Variations in survival for invasive cervical cancer among European women, 1978-89. Cancer Causes and Control, 10(6), 575-581. https://doi.org/10.1023/A:1008959211777

Variations in survival for invasive cervical cancer among European women, 1978-89. / Gatta, G.; Capocaccia, R.; Hakulinen, T.; Sant, L.; Verdecchia, A.; De Angelis, G.; Micheli, A.; Berrino, F.; Oberaigner, W.; Storm, H.; Aareleid, T.; Mace-Lesee'h, J.; Pottier, D.; Faivre, H.; Carli, P. M.; Chaplain, G.; Arveux, P.; Esteve, J.; Menegoz, F.; Raverdy, N.; Ziegler, H.; Tryggvadottir, L.; Tulinius, H.; Conti, E.; Vercelli, M.; Federico, M.; Mangone, L.; Ponz de Leon, M.; De Lisi, V.; Zanetti, R.; Gafa, L.; Tumino, R.; Falcini, F.; Barchielli, A.; Valente, F.; Pawlega, H.; Rachtan, J.; Bielska-Lasota, M.; Wronkowski, Z.; Obstnikova, A.; Plesko, I.; Pompe-Kirn, V.; Izarzugaza, I.; Viladiu, P.; Martinez-Garcia, C.; Garau, I.; Ardanaz, E.; Moreno, C.; Galceran, J.; Moller, T.; Torhurst, J.; Bouchardy, C.; Raymond, L.; Coebergh, J. W W; Damius, R.; Gould, A.; Black, R. J.; Davies, T. W.; Stockton, D.; Coleman, M. P.; Williams, E. M I; Littler, J.; Forman, D.; Quinn, M. J.; Roche, M.; Smith, J.; Bell, J.; Lawrence, G.

In: Cancer Causes and Control, Vol. 10, No. 6, 1999, p. 575-581.

Research output: Contribution to journalArticle

Gatta, G, Capocaccia, R, Hakulinen, T, Sant, L, Verdecchia, A, De Angelis, G, Micheli, A, Berrino, F, Oberaigner, W, Storm, H, Aareleid, T, Mace-Lesee'h, J, Pottier, D, Faivre, H, Carli, PM, Chaplain, G, Arveux, P, Esteve, J, Menegoz, F, Raverdy, N, Ziegler, H, Tryggvadottir, L, Tulinius, H, Conti, E, Vercelli, M, Federico, M, Mangone, L, Ponz de Leon, M, De Lisi, V, Zanetti, R, Gafa, L, Tumino, R, Falcini, F, Barchielli, A, Valente, F, Pawlega, H, Rachtan, J, Bielska-Lasota, M, Wronkowski, Z, Obstnikova, A, Plesko, I, Pompe-Kirn, V, Izarzugaza, I, Viladiu, P, Martinez-Garcia, C, Garau, I, Ardanaz, E, Moreno, C, Galceran, J, Moller, T, Torhurst, J, Bouchardy, C, Raymond, L, Coebergh, JWW, Damius, R, Gould, A, Black, RJ, Davies, TW, Stockton, D, Coleman, MP, Williams, EMI, Littler, J, Forman, D, Quinn, MJ, Roche, M, Smith, J, Bell, J & Lawrence, G 1999, 'Variations in survival for invasive cervical cancer among European women, 1978-89', Cancer Causes and Control, vol. 10, no. 6, pp. 575-581. https://doi.org/10.1023/A:1008959211777
Gatta, G. ; Capocaccia, R. ; Hakulinen, T. ; Sant, L. ; Verdecchia, A. ; De Angelis, G. ; Micheli, A. ; Berrino, F. ; Oberaigner, W. ; Storm, H. ; Aareleid, T. ; Mace-Lesee'h, J. ; Pottier, D. ; Faivre, H. ; Carli, P. M. ; Chaplain, G. ; Arveux, P. ; Esteve, J. ; Menegoz, F. ; Raverdy, N. ; Ziegler, H. ; Tryggvadottir, L. ; Tulinius, H. ; Conti, E. ; Vercelli, M. ; Federico, M. ; Mangone, L. ; Ponz de Leon, M. ; De Lisi, V. ; Zanetti, R. ; Gafa, L. ; Tumino, R. ; Falcini, F. ; Barchielli, A. ; Valente, F. ; Pawlega, H. ; Rachtan, J. ; Bielska-Lasota, M. ; Wronkowski, Z. ; Obstnikova, A. ; Plesko, I. ; Pompe-Kirn, V. ; Izarzugaza, I. ; Viladiu, P. ; Martinez-Garcia, C. ; Garau, I. ; Ardanaz, E. ; Moreno, C. ; Galceran, J. ; Moller, T. ; Torhurst, J. ; Bouchardy, C. ; Raymond, L. ; Coebergh, J. W W ; Damius, R. ; Gould, A. ; Black, R. J. ; Davies, T. W. ; Stockton, D. ; Coleman, M. P. ; Williams, E. M I ; Littler, J. ; Forman, D. ; Quinn, M. J. ; Roche, M. ; Smith, J. ; Bell, J. ; Lawrence, G. / Variations in survival for invasive cervical cancer among European women, 1978-89. In: Cancer Causes and Control. 1999 ; Vol. 10, No. 6. pp. 575-581.
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abstract = "Objectives: To analyze cervical cancer survival trends in 10 European countries using models that estimate the proportion of cured patients (having the same life expectancy as the general population) and the survival of fatal cases (who die from cervical cancel). Methods: We considered 40.906 cases diagnosed over 12 years (1978-89) collected from cancer registries participating in EUROCARE. Results: From 1978 to 1989, 5-year relative survival in Europe improved (60{\%}→63{\%}). The proportion of cured patients increased slightly but significantly (53{\%}→55{\%}, p = 0.05). For countries with poorer survival at the end of the 1970s the proportion of cured patients increased faster than average, particularly evident in England (49{\%}→56{\%}) and Scotland (44{\%}→53{\%}). By contrast, in Finland, Sweden and Germany with organized screening, 5-year survival and cure rate did not improve, but incidence declined to very low levels. Conclusions: Cervical screening can explain the trends in cervical cancer survival, this identifies premalignant lesions, reduces incidence and selectively prevents less aggressive cancers. The decreased proportion of the latter means that survival does not improve in countries with low incidence of cervical cancer. The increased proportion of cured patients with time shows that survival improvement was not due simply to earlier diagnosis with no patient advantage.",
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T1 - Variations in survival for invasive cervical cancer among European women, 1978-89

AU - Gatta, G.

AU - Capocaccia, R.

AU - Hakulinen, T.

AU - Sant, L.

AU - Verdecchia, A.

AU - De Angelis, G.

AU - Micheli, A.

AU - Berrino, F.

AU - Oberaigner, W.

AU - Storm, H.

AU - Aareleid, T.

AU - Mace-Lesee'h, J.

AU - Pottier, D.

AU - Faivre, H.

AU - Carli, P. M.

AU - Chaplain, G.

AU - Arveux, P.

AU - Esteve, J.

AU - Menegoz, F.

AU - Raverdy, N.

AU - Ziegler, H.

AU - Tryggvadottir, L.

AU - Tulinius, H.

AU - Conti, E.

AU - Vercelli, M.

AU - Federico, M.

AU - Mangone, L.

AU - Ponz de Leon, M.

AU - De Lisi, V.

AU - Zanetti, R.

AU - Gafa, L.

AU - Tumino, R.

AU - Falcini, F.

AU - Barchielli, A.

AU - Valente, F.

AU - Pawlega, H.

AU - Rachtan, J.

AU - Bielska-Lasota, M.

AU - Wronkowski, Z.

AU - Obstnikova, A.

AU - Plesko, I.

AU - Pompe-Kirn, V.

AU - Izarzugaza, I.

AU - Viladiu, P.

AU - Martinez-Garcia, C.

AU - Garau, I.

AU - Ardanaz, E.

AU - Moreno, C.

AU - Galceran, J.

AU - Moller, T.

AU - Torhurst, J.

AU - Bouchardy, C.

AU - Raymond, L.

AU - Coebergh, J. W W

AU - Damius, R.

AU - Gould, A.

AU - Black, R. J.

AU - Davies, T. W.

AU - Stockton, D.

AU - Coleman, M. P.

AU - Williams, E. M I

AU - Littler, J.

AU - Forman, D.

AU - Quinn, M. J.

AU - Roche, M.

AU - Smith, J.

AU - Bell, J.

AU - Lawrence, G.

PY - 1999

Y1 - 1999

N2 - Objectives: To analyze cervical cancer survival trends in 10 European countries using models that estimate the proportion of cured patients (having the same life expectancy as the general population) and the survival of fatal cases (who die from cervical cancel). Methods: We considered 40.906 cases diagnosed over 12 years (1978-89) collected from cancer registries participating in EUROCARE. Results: From 1978 to 1989, 5-year relative survival in Europe improved (60%→63%). The proportion of cured patients increased slightly but significantly (53%→55%, p = 0.05). For countries with poorer survival at the end of the 1970s the proportion of cured patients increased faster than average, particularly evident in England (49%→56%) and Scotland (44%→53%). By contrast, in Finland, Sweden and Germany with organized screening, 5-year survival and cure rate did not improve, but incidence declined to very low levels. Conclusions: Cervical screening can explain the trends in cervical cancer survival, this identifies premalignant lesions, reduces incidence and selectively prevents less aggressive cancers. The decreased proportion of the latter means that survival does not improve in countries with low incidence of cervical cancer. The increased proportion of cured patients with time shows that survival improvement was not due simply to earlier diagnosis with no patient advantage.

AB - Objectives: To analyze cervical cancer survival trends in 10 European countries using models that estimate the proportion of cured patients (having the same life expectancy as the general population) and the survival of fatal cases (who die from cervical cancel). Methods: We considered 40.906 cases diagnosed over 12 years (1978-89) collected from cancer registries participating in EUROCARE. Results: From 1978 to 1989, 5-year relative survival in Europe improved (60%→63%). The proportion of cured patients increased slightly but significantly (53%→55%, p = 0.05). For countries with poorer survival at the end of the 1970s the proportion of cured patients increased faster than average, particularly evident in England (49%→56%) and Scotland (44%→53%). By contrast, in Finland, Sweden and Germany with organized screening, 5-year survival and cure rate did not improve, but incidence declined to very low levels. Conclusions: Cervical screening can explain the trends in cervical cancer survival, this identifies premalignant lesions, reduces incidence and selectively prevents less aggressive cancers. The decreased proportion of the latter means that survival does not improve in countries with low incidence of cervical cancer. The increased proportion of cured patients with time shows that survival improvement was not due simply to earlier diagnosis with no patient advantage.

KW - Cervical cancer

KW - Cured patients

KW - Europe

KW - Population-based cancer registries

KW - Relative survival

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U2 - 10.1023/A:1008959211777

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