Variations in the age-specific curves of human papillomavirus prevalence in women worldwide

Silvia Franceschi, Rolando Herrero, Gary M. Clifford, Peter J F Snijders, Annie Arslan, Pham Thi Hoang Anh, F. Xavier Bosch, Catterina Ferreccio, Nguyen Trong Hieu, Eduardo Lazcano-Ponce, Elena Matos, Monica Molano, You Lin Qiao, Raj Rajkumar, Guglielmo Ronco, Silvia De Sanjosé, Hai Rim Shin, Sukhon Sukvirach, Jaiye O. Thomas, Chris J L M MeijerNubia Munoz, Miguel Angel Prince, Lily Herrera, Dora Loria, Amaranta Luzoro, José Manuel Ojeda, Rodrigo Prado, Ruide Huang, Shuli Shao, Hector Posso, Margarita Ronderos, Min Dai, Martyn Plummer, Jennifer S. Smith, Salvatore Vaccarella, Valeria Ghisetti, Anna Gillio-Tos, Silvano Gallus, Nereo Segnan, Duk Hee Lee, Mauricio Hernández-Avila, Akinyinka Omigbodun, Kunle Ojemakinde, Rebecca Font, Apichai Deechaisate, Vitaya Kesararat, Sirirat Tunsakul, Pipat Yingseri, Marcel Jacobs

Research output: Contribution to journalArticle

279 Citations (Scopus)

Abstract

An inverse relationship between age and human papillomavirus (HPV) prevalence has been reported in many developed countries, but information on this relationship is scarce in many other parts of the world. We carried out a cross-sectional study of sexually active women from the general population of 15 areas in 4 continents. Similar standardised protocols for women's enrolment, cervical specimen collection and PCR-based assays for HPV testing were used. HPV prevalence in different age groups was compared by study area. 18,498 women aged 15-74 years were included. Age-standardised HPV prevalence varied more than 10-fold between populations, as did the shape of age-specific curves. HPV prevalence peaked below age 25 or 35, and declined with age in Italy, the Netherlands, Spain, Argentina, Korea and in Lampang, Thailand and Ho Chi Minh, Vietnam. This was not the case in Songkla, Thailand nor Hanoi, Vietnam, where HPV prevalence was low in all age groups. In Chile, Colombia and Mexico, a second peak of HPV prevalence was detected among older women. In the poorest study areas in Asia (Shanxi, China and Dindigul, India), and in Nigeria, HPV prevalence was high across all age groups. The substantial differences observed in age-specific curves of HPV prevalence between populations may have a variety of explanations. These differences, however, underline that great caution should be used in inferring the natural history of HPV from age-specific prevalences.

Original languageEnglish
Pages (from-to)2677-2684
Number of pages8
JournalInternational Journal of Cancer
Volume119
Issue number11
DOIs
Publication statusPublished - Dec 1 2006

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Age Groups
Vietnam
Thailand
Population
Specimen Handling
Colombia
Chile
Argentina
Korea
Nigeria
Mexico
Natural History
Developed Countries
Netherlands
Spain
Italy
India
China
Cross-Sectional Studies
Polymerase Chain Reaction

Keywords

  • Age-specific curves
  • Human papillomavirus
  • Prevalence
  • Sexual habits

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Franceschi, S., Herrero, R., Clifford, G. M., Snijders, P. J. F., Arslan, A., Anh, P. T. H., ... Jacobs, M. (2006). Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. International Journal of Cancer, 119(11), 2677-2684. https://doi.org/10.1002/ijc.22241

Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. / Franceschi, Silvia; Herrero, Rolando; Clifford, Gary M.; Snijders, Peter J F; Arslan, Annie; Anh, Pham Thi Hoang; Bosch, F. Xavier; Ferreccio, Catterina; Hieu, Nguyen Trong; Lazcano-Ponce, Eduardo; Matos, Elena; Molano, Monica; Qiao, You Lin; Rajkumar, Raj; Ronco, Guglielmo; De Sanjosé, Silvia; Shin, Hai Rim; Sukvirach, Sukhon; Thomas, Jaiye O.; Meijer, Chris J L M; Munoz, Nubia; Prince, Miguel Angel; Herrera, Lily; Loria, Dora; Luzoro, Amaranta; Ojeda, José Manuel; Prado, Rodrigo; Huang, Ruide; Shao, Shuli; Posso, Hector; Ronderos, Margarita; Dai, Min; Plummer, Martyn; Smith, Jennifer S.; Vaccarella, Salvatore; Ghisetti, Valeria; Gillio-Tos, Anna; Gallus, Silvano; Segnan, Nereo; Lee, Duk Hee; Hernández-Avila, Mauricio; Omigbodun, Akinyinka; Ojemakinde, Kunle; Font, Rebecca; Deechaisate, Apichai; Kesararat, Vitaya; Tunsakul, Sirirat; Yingseri, Pipat; Jacobs, Marcel.

In: International Journal of Cancer, Vol. 119, No. 11, 01.12.2006, p. 2677-2684.

Research output: Contribution to journalArticle

Franceschi, S, Herrero, R, Clifford, GM, Snijders, PJF, Arslan, A, Anh, PTH, Bosch, FX, Ferreccio, C, Hieu, NT, Lazcano-Ponce, E, Matos, E, Molano, M, Qiao, YL, Rajkumar, R, Ronco, G, De Sanjosé, S, Shin, HR, Sukvirach, S, Thomas, JO, Meijer, CJLM, Munoz, N, Prince, MA, Herrera, L, Loria, D, Luzoro, A, Ojeda, JM, Prado, R, Huang, R, Shao, S, Posso, H, Ronderos, M, Dai, M, Plummer, M, Smith, JS, Vaccarella, S, Ghisetti, V, Gillio-Tos, A, Gallus, S, Segnan, N, Lee, DH, Hernández-Avila, M, Omigbodun, A, Ojemakinde, K, Font, R, Deechaisate, A, Kesararat, V, Tunsakul, S, Yingseri, P & Jacobs, M 2006, 'Variations in the age-specific curves of human papillomavirus prevalence in women worldwide', International Journal of Cancer, vol. 119, no. 11, pp. 2677-2684. https://doi.org/10.1002/ijc.22241
Franceschi S, Herrero R, Clifford GM, Snijders PJF, Arslan A, Anh PTH et al. Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. International Journal of Cancer. 2006 Dec 1;119(11):2677-2684. https://doi.org/10.1002/ijc.22241
Franceschi, Silvia ; Herrero, Rolando ; Clifford, Gary M. ; Snijders, Peter J F ; Arslan, Annie ; Anh, Pham Thi Hoang ; Bosch, F. Xavier ; Ferreccio, Catterina ; Hieu, Nguyen Trong ; Lazcano-Ponce, Eduardo ; Matos, Elena ; Molano, Monica ; Qiao, You Lin ; Rajkumar, Raj ; Ronco, Guglielmo ; De Sanjosé, Silvia ; Shin, Hai Rim ; Sukvirach, Sukhon ; Thomas, Jaiye O. ; Meijer, Chris J L M ; Munoz, Nubia ; Prince, Miguel Angel ; Herrera, Lily ; Loria, Dora ; Luzoro, Amaranta ; Ojeda, José Manuel ; Prado, Rodrigo ; Huang, Ruide ; Shao, Shuli ; Posso, Hector ; Ronderos, Margarita ; Dai, Min ; Plummer, Martyn ; Smith, Jennifer S. ; Vaccarella, Salvatore ; Ghisetti, Valeria ; Gillio-Tos, Anna ; Gallus, Silvano ; Segnan, Nereo ; Lee, Duk Hee ; Hernández-Avila, Mauricio ; Omigbodun, Akinyinka ; Ojemakinde, Kunle ; Font, Rebecca ; Deechaisate, Apichai ; Kesararat, Vitaya ; Tunsakul, Sirirat ; Yingseri, Pipat ; Jacobs, Marcel. / Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. In: International Journal of Cancer. 2006 ; Vol. 119, No. 11. pp. 2677-2684.
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