Variazioni della sensibilità agli antibiotici di alcuni ceppi batterici dopo contatto con metalli impiegati per la costruzione di impianti protesici.

Translated title of the contribution: Variations in the antibiotic sensitivity of bacterial strains after contact with the metals used for the construction of prosthetic implants

E. Cenni, A. Andollina, C. R. Arciola, M. Cervellati, G. Bertoni, D. Cavedagna, A. Pizzoferrato

Research output: Contribution to journalArticle


The antibiotic sensitivity of 19 Gram-positive bacterial strains (11 Staphylococcus aureus and 8 Staphylococcus epidermidis) and 16 Gram-negative strains (8 Escherichia coli and 8 Proteus species) was evaluated after contact with stainless steel and with some metals compounding the alloys used for prosthetic devices. The hypothesis was that the resistance to antibiotic therapy of infections associated with prosthetic implants is also due to a modification in the sensitivity of microorganisms. The results, compared to those obtained from control tests, showed only slight variations in the antibiotic sensitivity of the strains put in contact with the metals. In Gram-positive strains, after contact with metals, the increase in sensitivity occurred more frequently than the reduction. In Gram-negative strains, the decrease in sensitivity was more frequent than the increase. Proteus strains showed sensitivity variations more frequently than Escherichia coli strains. Titanium and nickel induced the highest number of variations, both in Gram-positive and Gram-negative strains.

Original languageItalian
Pages (from-to)422-428
Number of pages7
JournalGiornale di Chirurgia
Issue number10
Publication statusPublished - Oct 1994


ASJC Scopus subject areas

  • Surgery

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