TY - JOUR
T1 - Varicella associated pneumoniae in a pediatric population
AU - Bozzola, Elena
AU - Gattinara, Guido Castelli
AU - Bozzola, Mauro
AU - Mirante, Nadia
AU - Masci, Marco
AU - Rossetti, Chiara
AU - Krzystofiak, Andrzej
AU - Nicolosi, Luciana
AU - Cutrera, Renato
AU - Lancella, Laura
AU - Tozzi, Alberto Eugenio
AU - Villani, Alberto
PY - 2017/5/30
Y1 - 2017/5/30
N2 - Background: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization. Methods: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period. Results: Pneumonia occurred in 8.2% of children hospitalized for varicella. The median length of hospitalization was 6 days. No statistically significant difference in length of stay was detected between immunodepressed children and previously healthy children. The hospitalization was on average shorter in patients who started antiviral therapy within 24 h of varicella onset. None of the included patients had been previously immunized for varicella. Conclusions: Our results support the need for increased awareness of current varicella prevention recommendations among both immunocompetent and immunodepressed individuals. In children affected by varicella, prompt antiviral therapy may be indicated to reduce the number of days of hospitalization.
AB - Background: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization. Methods: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period. Results: Pneumonia occurred in 8.2% of children hospitalized for varicella. The median length of hospitalization was 6 days. No statistically significant difference in length of stay was detected between immunodepressed children and previously healthy children. The hospitalization was on average shorter in patients who started antiviral therapy within 24 h of varicella onset. None of the included patients had been previously immunized for varicella. Conclusions: Our results support the need for increased awareness of current varicella prevention recommendations among both immunocompetent and immunodepressed individuals. In children affected by varicella, prompt antiviral therapy may be indicated to reduce the number of days of hospitalization.
KW - children
KW - hospitalization
KW - pneumoniae complication
KW - vaccine
KW - Varicella
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U2 - 10.1186/s13052-017-0366-8
DO - 10.1186/s13052-017-0366-8
M3 - Article
AN - SCOPUS:85019717449
VL - 43
JO - Italian Journal of Pediatrics
JF - Italian Journal of Pediatrics
SN - 1720-8424
IS - 1
M1 - 49
ER -