Vascular endothelium summary statement III: Cancer prevention and control

Eddie Reed, John Seffrin, Raffaella Giavazzi, Victor van Hinsbergh, Paolo Madeddu

Research output: Contribution to journalArticlepeer-review

Abstract

The biology of vascular endothelium can be modulated through the use of pharmacologic agents. Whereas this has been explored to reasonable extent in cardiovascular disease, it is clear that the ability to modulate vascular endothelium for the purpose of cancer prevention is in its early stages. Among the unanswered questions, we do not understand under what circumstances such pharmacologic interventions might best be started; nor, how long such interventions might be used for a given individual. We present concepts for further exploration in the use of endothelial-active agents for cancer prevention and control; and, strategies for public health practice and research in this area.

Original languageEnglish
Pages (from-to)321-323
Number of pages3
JournalVascular Pharmacology
Volume46
Issue number5 SPEC. ISS.
DOIs
Publication statusPublished - May 2007

Keywords

  • Angiogenesis
  • Cancer prevention
  • Endothelial cells

ASJC Scopus subject areas

  • Pharmacology

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