Vascular impairment in patients with primary biliary cirrhosis.

B. Marasini, C. Pipia, G. DeValle, A. Crosignani, L. Petroni, M. Cugno, S. Zeni, S. Bruno, C. Bassani

Research output: Contribution to journalArticlepeer-review


Experimental and clinical observation suggest that patients with primary biliary cirrhosis (PBC) have endothelial dysfunction. Postischemic digital blood flow, nailfold capillaroscopy, von Willebrand factor (vWf) and tissue-type plasminogen activator (t-PA) plasma levels were examined in 59 PBC patients. Forty-six subjects (15 with liver diseases other than PBC, 11 hypercholesterolemics, 20 healthy subjects) served as controls. PBC versus healthy controls (209.8 +/- 1.4% and 16.54 +/- 1.44 ng/ml vs. 120.2 +/- 1.4% and 9.91 +/- 1.49 ng/ml; p

Original languageEnglish
Pages (from-to)75-79
Number of pages5
JournalInternational journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation
Issue number2
Publication statusPublished - Mar 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology


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