Vascular risk factors, alcohol intake, and cognitive decline

F. Panza, C. Capurso, A. D'Introno, A. M. Colacicco, V. Frisardi, A. Santamato, M. Ranieri, P. Fiore, G. Vendemiale, D. Seripa, A. Pilotto, A. Capurso, V. Solfrizzi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Since the therapeutic options currently available have demonstrated limited efficacy, the search for preventive strategies for cognitive decline and dementia is mandatory, A possible role of vascular and lifestyle-related factors was recently proposed for age-related changes of cognitive function, predementia syndromes, and cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin. At present, cumulative evidence suggested that vascular risk factors may be important in the development of mild cognitive impairment (MCI), dementia, and AD. Among vascular-related factors, metabolic syndrome has been associated with the risk of cognitive decline and overall dementia. Moderate alcohol drinking has been proposed as a protective factor against MCI and dementia in several longitudinal studies, but contrasting findings also exist. However, in most cases, these were only observational studies, and results are awaited from large multicenter randomized clinical trials in older persons. At present, vascular risk factor management, lifestyle changes, and drugs could be employed together to delay the onset of dementia syndromes.

Original languageEnglish
Pages (from-to)376-381
Number of pages6
JournalJournal of Nutrition, Health and Aging
Volume12
Issue number6
DOIs
Publication statusPublished - Jun 2008

Fingerprint

dementia
blood vessels
Dementia
risk factors
Alcohols
Alzheimer disease
lifestyle
Blood Vessels
Life Style
Alzheimer Disease
randomized clinical trials
metabolic syndrome
Risk Management
observational studies
longitudinal studies
cognition
Alcohol Drinking
Cognition
Observational Studies
Longitudinal Studies

Keywords

  • Alcohol
  • Alzheimer's disease
  • Dementia
  • Metabolic syndrome
  • Mild cognitive impairment
  • Predementia syndromes
  • Vascular dementia
  • Vascular risk factors

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Ageing
  • Endocrinology
  • Food Science

Cite this

Panza, F., Capurso, C., D'Introno, A., Colacicco, A. M., Frisardi, V., Santamato, A., ... Solfrizzi, V. (2008). Vascular risk factors, alcohol intake, and cognitive decline. Journal of Nutrition, Health and Aging, 12(6), 376-381. https://doi.org/10.1007/BF02982669

Vascular risk factors, alcohol intake, and cognitive decline. / Panza, F.; Capurso, C.; D'Introno, A.; Colacicco, A. M.; Frisardi, V.; Santamato, A.; Ranieri, M.; Fiore, P.; Vendemiale, G.; Seripa, D.; Pilotto, A.; Capurso, A.; Solfrizzi, V.

In: Journal of Nutrition, Health and Aging, Vol. 12, No. 6, 06.2008, p. 376-381.

Research output: Contribution to journalArticle

Panza, F, Capurso, C, D'Introno, A, Colacicco, AM, Frisardi, V, Santamato, A, Ranieri, M, Fiore, P, Vendemiale, G, Seripa, D, Pilotto, A, Capurso, A & Solfrizzi, V 2008, 'Vascular risk factors, alcohol intake, and cognitive decline', Journal of Nutrition, Health and Aging, vol. 12, no. 6, pp. 376-381. https://doi.org/10.1007/BF02982669
Panza F, Capurso C, D'Introno A, Colacicco AM, Frisardi V, Santamato A et al. Vascular risk factors, alcohol intake, and cognitive decline. Journal of Nutrition, Health and Aging. 2008 Jun;12(6):376-381. https://doi.org/10.1007/BF02982669
Panza, F. ; Capurso, C. ; D'Introno, A. ; Colacicco, A. M. ; Frisardi, V. ; Santamato, A. ; Ranieri, M. ; Fiore, P. ; Vendemiale, G. ; Seripa, D. ; Pilotto, A. ; Capurso, A. ; Solfrizzi, V. / Vascular risk factors, alcohol intake, and cognitive decline. In: Journal of Nutrition, Health and Aging. 2008 ; Vol. 12, No. 6. pp. 376-381.
@article{95f3a3cf6b5b43ff904c5fea5ce4bd82,
title = "Vascular risk factors, alcohol intake, and cognitive decline",
abstract = "Since the therapeutic options currently available have demonstrated limited efficacy, the search for preventive strategies for cognitive decline and dementia is mandatory, A possible role of vascular and lifestyle-related factors was recently proposed for age-related changes of cognitive function, predementia syndromes, and cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin. At present, cumulative evidence suggested that vascular risk factors may be important in the development of mild cognitive impairment (MCI), dementia, and AD. Among vascular-related factors, metabolic syndrome has been associated with the risk of cognitive decline and overall dementia. Moderate alcohol drinking has been proposed as a protective factor against MCI and dementia in several longitudinal studies, but contrasting findings also exist. However, in most cases, these were only observational studies, and results are awaited from large multicenter randomized clinical trials in older persons. At present, vascular risk factor management, lifestyle changes, and drugs could be employed together to delay the onset of dementia syndromes.",
keywords = "Alcohol, Alzheimer's disease, Dementia, Metabolic syndrome, Mild cognitive impairment, Predementia syndromes, Vascular dementia, Vascular risk factors",
author = "F. Panza and C. Capurso and A. D'Introno and Colacicco, {A. M.} and V. Frisardi and A. Santamato and M. Ranieri and P. Fiore and G. Vendemiale and D. Seripa and A. Pilotto and A. Capurso and V. Solfrizzi",
year = "2008",
month = "6",
doi = "10.1007/BF02982669",
language = "English",
volume = "12",
pages = "376--381",
journal = "Journal of Nutrition, Health and Aging",
issn = "1279-7707",
publisher = "Springer Paris",
number = "6",

}

TY - JOUR

T1 - Vascular risk factors, alcohol intake, and cognitive decline

AU - Panza, F.

AU - Capurso, C.

AU - D'Introno, A.

AU - Colacicco, A. M.

AU - Frisardi, V.

AU - Santamato, A.

AU - Ranieri, M.

AU - Fiore, P.

AU - Vendemiale, G.

AU - Seripa, D.

AU - Pilotto, A.

AU - Capurso, A.

AU - Solfrizzi, V.

PY - 2008/6

Y1 - 2008/6

N2 - Since the therapeutic options currently available have demonstrated limited efficacy, the search for preventive strategies for cognitive decline and dementia is mandatory, A possible role of vascular and lifestyle-related factors was recently proposed for age-related changes of cognitive function, predementia syndromes, and cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin. At present, cumulative evidence suggested that vascular risk factors may be important in the development of mild cognitive impairment (MCI), dementia, and AD. Among vascular-related factors, metabolic syndrome has been associated with the risk of cognitive decline and overall dementia. Moderate alcohol drinking has been proposed as a protective factor against MCI and dementia in several longitudinal studies, but contrasting findings also exist. However, in most cases, these were only observational studies, and results are awaited from large multicenter randomized clinical trials in older persons. At present, vascular risk factor management, lifestyle changes, and drugs could be employed together to delay the onset of dementia syndromes.

AB - Since the therapeutic options currently available have demonstrated limited efficacy, the search for preventive strategies for cognitive decline and dementia is mandatory, A possible role of vascular and lifestyle-related factors was recently proposed for age-related changes of cognitive function, predementia syndromes, and cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin. At present, cumulative evidence suggested that vascular risk factors may be important in the development of mild cognitive impairment (MCI), dementia, and AD. Among vascular-related factors, metabolic syndrome has been associated with the risk of cognitive decline and overall dementia. Moderate alcohol drinking has been proposed as a protective factor against MCI and dementia in several longitudinal studies, but contrasting findings also exist. However, in most cases, these were only observational studies, and results are awaited from large multicenter randomized clinical trials in older persons. At present, vascular risk factor management, lifestyle changes, and drugs could be employed together to delay the onset of dementia syndromes.

KW - Alcohol

KW - Alzheimer's disease

KW - Dementia

KW - Metabolic syndrome

KW - Mild cognitive impairment

KW - Predementia syndromes

KW - Vascular dementia

KW - Vascular risk factors

UR - http://www.scopus.com/inward/record.url?scp=46849094932&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=46849094932&partnerID=8YFLogxK

U2 - 10.1007/BF02982669

DO - 10.1007/BF02982669

M3 - Article

C2 - 18548174

AN - SCOPUS:46849094932

VL - 12

SP - 376

EP - 381

JO - Journal of Nutrition, Health and Aging

JF - Journal of Nutrition, Health and Aging

SN - 1279-7707

IS - 6

ER -