Abstract
Background To review vascularized-pigment epithelial detachment (V-PED) treatment visual outcome, and to assess acute retinal pigment epithelium (RPE) tear incidence. Methods One hundred and thirty-two eyes of 125 consecutive patients with age-related macular degeneration and V-PED were included. Ninety-four eyes (71.2%) were associated with choroidal new vessels (CNV), 38 (28.8%) with retinal angiomatous proliferation (RAP). Patients, treated over a 10-year period with the time-current therapy, received: verteporfin photodynamic therapy (PDT) (group 1, 38 eyes), combined intravitreal triamcinolone acetonide (IVTA) and PDT (group 2, 44 eyes) or intravitreal anti-VEGF injection (bevacizumab or ranibizumab) (group 3, 50 eyes). Results Mean follow-up was 20.5 months. At month 12, all eyes treated with PDTor with IVTA and PDTshowed a mean significant severe visual decrease. Eyes with CNV lost -0.67 and -0.37 logMAR (p
Original language | English |
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Pages (from-to) | 1283-1292 |
Number of pages | 10 |
Journal | Graefe's Archive for Clinical and Experimental Ophthalmology |
Volume | 250 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sep 2012 |
Keywords
- Age-related macular degeneration
- Antivegf
- Choroidal neovascularization
- Retinal angiomatous proliferation
- Retinal pigment epithelial detachment
- Rpe tear
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience