Vascularized retinal pigment epithelial detachment in age-related macular degeneration: Treatment and RPE tear incidence

Ugo Introini, Ana Torres Gimeno, Fabrizio Scotti, Marco Setaccioli, Silvia Giatsidis, Francesco Bandello

Research output: Contribution to journalArticlepeer-review

Abstract

Background To review vascularized-pigment epithelial detachment (V-PED) treatment visual outcome, and to assess acute retinal pigment epithelium (RPE) tear incidence. Methods One hundred and thirty-two eyes of 125 consecutive patients with age-related macular degeneration and V-PED were included. Ninety-four eyes (71.2%) were associated with choroidal new vessels (CNV), 38 (28.8%) with retinal angiomatous proliferation (RAP). Patients, treated over a 10-year period with the time-current therapy, received: verteporfin photodynamic therapy (PDT) (group 1, 38 eyes), combined intravitreal triamcinolone acetonide (IVTA) and PDT (group 2, 44 eyes) or intravitreal anti-VEGF injection (bevacizumab or ranibizumab) (group 3, 50 eyes). Results Mean follow-up was 20.5 months. At month 12, all eyes treated with PDTor with IVTA and PDTshowed a mean significant severe visual decrease. Eyes with CNV lost -0.67 and -0.37 logMAR (p

Original languageEnglish
Pages (from-to)1283-1292
Number of pages10
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume250
Issue number9
DOIs
Publication statusPublished - Sep 2012

Keywords

  • Age-related macular degeneration
  • Antivegf
  • Choroidal neovascularization
  • Retinal angiomatous proliferation
  • Retinal pigment epithelial detachment
  • Rpe tear

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Vascularized retinal pigment epithelial detachment in age-related macular degeneration: Treatment and RPE tear incidence'. Together they form a unique fingerprint.

Cite this