VATS-US1: Thoracoscopic ultrasonography for the identification of nodules during lung metastasectomy

Francesco Londero, Luigi Castriotta, William Grossi, Gianluca Masullo, Angelo Morelli, Cecilia Tetta, Ugolino Livi, Jos G Maessen, Sandro Gelsomino

Research output: Contribution to journalArticlepeer-review


Open thoracotomy during pulmonary metastasectomy allows lung palpation and may discover unexpected further nodules. We assess the validity of intraoperative lung ultrasonography via thoracoscopy in identifying lung nodules. A first surgeon will perform an ultrasonographic investigation on the deflated lung by thoracoscopy. A second surgeon will then perform a manual exploration of the organ by thoracotomy. Data on number and localization of nodules will be matched and compared with final histology report. Sensitivity and specificity will be assessed. Concordance will be assessed with Cohen K test. Calculated sample size is 89 patients. This study might have an important role in shifting the surgical practice towards a less invasive approach, with consequent benefits for the patient. Protocol is registered on Protocol registration number: NCT03864874.

Original languageEnglish
Pages (from-to)85-89
Number of pages5
JournalFuture Oncology
Issue number5
Publication statusPublished - Feb 2020


  • VATS
  • lung metastases
  • ultrasound


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