Abstract
Background: The prevalence of venous thrombosis (VT) in children with solid tumor and the role of different risk factors are not defined yet. Aim: A cross-sectional observational study was conducted to evaluate the prevalence of both symptomatic and asymptomatic catheter-associated thrombosis events in children affected with different solid tumors. Methods: Patients with a solid tumor, admitted as day-care, were consecutively enrolled over a period of 10 months. All of them had a central venous line. Physical examination, D-dimer serum tests, and eco-color-Doppler ultrasonography were performed once at any time before catheter removal. Results: Forty-two patients (14 females and 28 males)-mean age 115 months-were evaluated. Five of the 42 patients (12%) had VT. In 4 of these, VT was catheter-related: 3 asymptomatic and 1 symptomatic. In the last patient, VT was clinically symptomatic and not catheter related. Patients with longer duration of catheter insertion presented with a higher rate of VT (P=0.05). Moreover, patients affected with neuroblastoma showed a higher rate of VT than the others with different solid tumors (P
| Original language | English |
|---|---|
| Pages (from-to) | 148-152 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Hematology/Oncology |
| Volume | 30 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2008 |
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Keywords
- Children
- Solid tumor
- Thrombosis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Oncology
- Hematology
Cite this
Venous thrombosis in children with solid tumors. / Schiavetti, Amalia; Foco, Micaela; Ingrosso, Annapaola; Bonci, Enea; Conti, Laura; Matrunola, Marco.
In: Journal of Pediatric Hematology/Oncology, Vol. 30, No. 2, 02.2008, p. 148-152.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Venous thrombosis in children with solid tumors
AU - Schiavetti, Amalia
AU - Foco, Micaela
AU - Ingrosso, Annapaola
AU - Bonci, Enea
AU - Conti, Laura
AU - Matrunola, Marco
PY - 2008/2
Y1 - 2008/2
N2 - Background: The prevalence of venous thrombosis (VT) in children with solid tumor and the role of different risk factors are not defined yet. Aim: A cross-sectional observational study was conducted to evaluate the prevalence of both symptomatic and asymptomatic catheter-associated thrombosis events in children affected with different solid tumors. Methods: Patients with a solid tumor, admitted as day-care, were consecutively enrolled over a period of 10 months. All of them had a central venous line. Physical examination, D-dimer serum tests, and eco-color-Doppler ultrasonography were performed once at any time before catheter removal. Results: Forty-two patients (14 females and 28 males)-mean age 115 months-were evaluated. Five of the 42 patients (12%) had VT. In 4 of these, VT was catheter-related: 3 asymptomatic and 1 symptomatic. In the last patient, VT was clinically symptomatic and not catheter related. Patients with longer duration of catheter insertion presented with a higher rate of VT (P=0.05). Moreover, patients affected with neuroblastoma showed a higher rate of VT than the others with different solid tumors (P
AB - Background: The prevalence of venous thrombosis (VT) in children with solid tumor and the role of different risk factors are not defined yet. Aim: A cross-sectional observational study was conducted to evaluate the prevalence of both symptomatic and asymptomatic catheter-associated thrombosis events in children affected with different solid tumors. Methods: Patients with a solid tumor, admitted as day-care, were consecutively enrolled over a period of 10 months. All of them had a central venous line. Physical examination, D-dimer serum tests, and eco-color-Doppler ultrasonography were performed once at any time before catheter removal. Results: Forty-two patients (14 females and 28 males)-mean age 115 months-were evaluated. Five of the 42 patients (12%) had VT. In 4 of these, VT was catheter-related: 3 asymptomatic and 1 symptomatic. In the last patient, VT was clinically symptomatic and not catheter related. Patients with longer duration of catheter insertion presented with a higher rate of VT (P=0.05). Moreover, patients affected with neuroblastoma showed a higher rate of VT than the others with different solid tumors (P
KW - Children
KW - Solid tumor
KW - Thrombosis
UR - http://www.scopus.com/inward/record.url?scp=41949109535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=41949109535&partnerID=8YFLogxK
U2 - 10.1097/MPH.0b013e31815f88b7
DO - 10.1097/MPH.0b013e31815f88b7
M3 - Article
C2 - 18376268
AN - SCOPUS:41949109535
VL - 30
SP - 148
EP - 152
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
SN - 1077-4114
IS - 2
ER -