Venous thrombosis in children with solid tumors

Amalia Schiavetti, Micaela Foco, Annapaola Ingrosso, Enea Bonci, Laura Conti, Marco Matrunola

Research output: Contribution to journalArticle

Abstract

Background: The prevalence of venous thrombosis (VT) in children with solid tumor and the role of different risk factors are not defined yet. Aim: A cross-sectional observational study was conducted to evaluate the prevalence of both symptomatic and asymptomatic catheter-associated thrombosis events in children affected with different solid tumors. Methods: Patients with a solid tumor, admitted as day-care, were consecutively enrolled over a period of 10 months. All of them had a central venous line. Physical examination, D-dimer serum tests, and eco-color-Doppler ultrasonography were performed once at any time before catheter removal. Results: Forty-two patients (14 females and 28 males)-mean age 115 months-were evaluated. Five of the 42 patients (12%) had VT. In 4 of these, VT was catheter-related: 3 asymptomatic and 1 symptomatic. In the last patient, VT was clinically symptomatic and not catheter related. Patients with longer duration of catheter insertion presented with a higher rate of VT (P=0.05). Moreover, patients affected with neuroblastoma showed a higher rate of VT than the others with different solid tumors (P

Original languageEnglish
Pages (from-to)148-152
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Volume30
Issue number2
DOIs
Publication statusPublished - Feb 2008

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Venous Thrombosis
Catheters
Neoplasms
Doppler Color Ultrasonography
Neuroblastoma
Physical Examination
Observational Studies
Thrombosis
Cross-Sectional Studies
Serum

Keywords

  • Children
  • Solid tumor
  • Thrombosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Schiavetti, A., Foco, M., Ingrosso, A., Bonci, E., Conti, L., & Matrunola, M. (2008). Venous thrombosis in children with solid tumors. Journal of Pediatric Hematology/Oncology, 30(2), 148-152. https://doi.org/10.1097/MPH.0b013e31815f88b7

Venous thrombosis in children with solid tumors. / Schiavetti, Amalia; Foco, Micaela; Ingrosso, Annapaola; Bonci, Enea; Conti, Laura; Matrunola, Marco.

In: Journal of Pediatric Hematology/Oncology, Vol. 30, No. 2, 02.2008, p. 148-152.

Research output: Contribution to journalArticle

Schiavetti, A, Foco, M, Ingrosso, A, Bonci, E, Conti, L & Matrunola, M 2008, 'Venous thrombosis in children with solid tumors', Journal of Pediatric Hematology/Oncology, vol. 30, no. 2, pp. 148-152. https://doi.org/10.1097/MPH.0b013e31815f88b7
Schiavetti, Amalia ; Foco, Micaela ; Ingrosso, Annapaola ; Bonci, Enea ; Conti, Laura ; Matrunola, Marco. / Venous thrombosis in children with solid tumors. In: Journal of Pediatric Hematology/Oncology. 2008 ; Vol. 30, No. 2. pp. 148-152.
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