Ventricular arrhythmias and sympatho-vagal imbalance in congestive heart failure, are they related?

A. Mortara, M. T. La Rovere, P. Pantaleo, M. Pozzoli, G. Forni, E. Traversi, F. Cobelli, L. Tavazzi

Research output: Contribution to journalArticlepeer-review

Abstract

To assess the relationship among ventricular arrhythmias, hemodynamic profile and autonomic nervous system 82 patients with congestive heart failure (CHF) underwent 24 h ECG recording, right heart catheterization, baroreflex sensitivity (BRS) and heart rate variability (HRV) assessment. Patients with ventricular arrhythmias (VEBs > 10 h, couplets, NSVT) showed a significantly higher mean pulmonary artery (PAP) and pulmonary capillary (PCP) pressures as compared to patients without arrhythmias, while BRS and HRV were not significantly different. When CHF patients were grouped according to PCP > = o <18 mmHg a markedly reduced BRS and HRV were observed in arrhythmic as compared to non-arrhythmic patients in the group with higher PCP, while no differences were found in patients with PCP <18 mmHg. Conclusions: in our study ventricular arrhythmias are largely related to hemodynamics; in the more advanced stages of the disease the autonomic imbalance may play an additive role in the genesis of cardiac arrhythmias.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalNew Trends in Arrhythmias
Volume9
Issue number2
Publication statusPublished - 1993

Keywords

  • baroreflex sensitivity
  • congestive heart failure
  • heart rate variability
  • ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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