Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis

WS Tzou; R Tung; DS Frankel; M Vaseghi; T Jared Bunch; Luigi Di Biase; VN Tholakanahalli; D Lakkireddy; T Dickfeld; A Saliaris; J Peter Weiss; N Mathuria; U Tedrow; MR Afzal; P Vergara; K Nagashima; M Patel; S Nakahara; K Vakil; J David Burkhardt; CH Tseng; Andrea Natale; K Shivkumar; DJ Callans; WG Stevenson; P Della Bella; FE Marchlinski; WH Sauer

doi:10.1161/CIRCEP.116.004494

Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis

WS Tzou, R Tung, DS Frankel, M Vaseghi, T Jared Bunch, Luigi Di Biase, VN Tholakanahalli, D Lakkireddy, T Dickfeld, A Saliaris, J Peter Weiss, N Mathuria, U Tedrow, MR Afzal, P Vergara, K Nagashima, M Patel, S Nakahara, K Vakil, J David BurkhardtCH Tseng, Andrea Natale, K Shivkumar, DJ Callans, WG Stevenson, P Della Bella, FE Marchlinski, WH Sauer

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Background - Ventricular tachycardia (VT) radiofrequency ablation has been associated with reduced VT recurrence and mortality, although it is typically not considered among New York Heart Association class IV (NYHA IV) heart failure patients. We compared characteristics and VT radiofrequency ablation outcomes of those with and without NYHA IV in the International VT Ablation Center Collaboration. Methods and Results - NYHA II-IV patients undergoing VT radiofrequency ablation at 12 international centers were included. Clinical variables, VT recurrence, and mortality were analyzed by NYHA IV status using Kaplan-Meier analysis and Cox proportional hazard models. There were significant differences between NYHA IV (n=111) and NYHA II and III (n=1254) patients: NYHA IV had lower left ventricular ejection fraction; more had diabetes mellitus, kidney disease, cardiac resynchronization implantable cardioverter-defibrillator, and VT storm despite greater antiarrhythmic drug use (P

Original language	English
Article number	e004494
Journal	Circulation: Arrhythmia and Electrophysiology
Volume	10
Issue number	1
DOIs	https://doi.org/10.1161/CIRCEP.116.004494
Publication status	Published - 2017

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10.1161/CIRCEP.116.004494

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Tzou, WS., Tung, R., Frankel, DS., Vaseghi, M., Jared Bunch, T., Di Biase, L., Tholakanahalli, VN., Lakkireddy, D., Dickfeld, T., Saliaris, A., Peter Weiss, J., Mathuria, N., Tedrow, U., Afzal, MR., Vergara, P., Nagashima, K., Patel, M., Nakahara, S., Vakil, K., ... Sauer, WH. (2017). Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. Circulation: Arrhythmia and Electrophysiology, 10(1), [e004494]. https://doi.org/10.1161/CIRCEP.116.004494

Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. / Tzou, WS; Tung, R; Frankel, DS; Vaseghi, M; Jared Bunch, T; Di Biase, Luigi; Tholakanahalli, VN; Lakkireddy, D; Dickfeld, T; Saliaris, A; Peter Weiss, J; Mathuria, N; Tedrow, U; Afzal, MR; Vergara, P; Nagashima, K; Patel, M; Nakahara, S; Vakil, K; David Burkhardt, J; Tseng, CH; Natale, Andrea; Shivkumar, K; Callans, DJ; Stevenson, WG; Della Bella, P; Marchlinski, FE; Sauer, WH.

In: Circulation: Arrhythmia and Electrophysiology, Vol. 10, No. 1, e004494, 2017.

Research output: Contribution to journal › Article › peer-review

Tzou, WS, Tung, R, Frankel, DS, Vaseghi, M, Jared Bunch, T, Di Biase, L, Tholakanahalli, VN, Lakkireddy, D, Dickfeld, T, Saliaris, A, Peter Weiss, J, Mathuria, N, Tedrow, U, Afzal, MR, Vergara, P, Nagashima, K, Patel, M, Nakahara, S, Vakil, K, David Burkhardt, J, Tseng, CH, Natale, A, Shivkumar, K, Callans, DJ, Stevenson, WG, Della Bella, P, Marchlinski, FE & Sauer, WH 2017, 'Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis', Circulation: Arrhythmia and Electrophysiology, vol. 10, no. 1, e004494. https://doi.org/10.1161/CIRCEP.116.004494

Tzou, WS ; Tung, R ; Frankel, DS ; Vaseghi, M ; Jared Bunch, T ; Di Biase, Luigi ; Tholakanahalli, VN ; Lakkireddy, D ; Dickfeld, T ; Saliaris, A ; Peter Weiss, J ; Mathuria, N ; Tedrow, U ; Afzal, MR ; Vergara, P ; Nagashima, K ; Patel, M ; Nakahara, S ; Vakil, K ; David Burkhardt, J ; Tseng, CH ; Natale, Andrea ; Shivkumar, K ; Callans, DJ ; Stevenson, WG ; Della Bella, P ; Marchlinski, FE ; Sauer, WH. / Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. In: Circulation: Arrhythmia and Electrophysiology. 2017 ; Vol. 10, No. 1.

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title = "Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis",

abstract = "Background - Ventricular tachycardia (VT) radiofrequency ablation has been associated with reduced VT recurrence and mortality, although it is typically not considered among New York Heart Association class IV (NYHA IV) heart failure patients. We compared characteristics and VT radiofrequency ablation outcomes of those with and without NYHA IV in the International VT Ablation Center Collaboration. Methods and Results - NYHA II-IV patients undergoing VT radiofrequency ablation at 12 international centers were included. Clinical variables, VT recurrence, and mortality were analyzed by NYHA IV status using Kaplan-Meier analysis and Cox proportional hazard models. There were significant differences between NYHA IV (n=111) and NYHA II and III (n=1254) patients: NYHA IV had lower left ventricular ejection fraction; more had diabetes mellitus, kidney disease, cardiac resynchronization implantable cardioverter-defibrillator, and VT storm despite greater antiarrhythmic drug use (P",

author = "WS Tzou and R Tung and DS Frankel and M Vaseghi and {Jared Bunch}, T and {Di Biase}, Luigi and VN Tholakanahalli and D Lakkireddy and T Dickfeld and A Saliaris and {Peter Weiss}, J and N Mathuria and U Tedrow and MR Afzal and P Vergara and K Nagashima and M Patel and S Nakahara and K Vakil and {David Burkhardt}, J and CH Tseng and Andrea Natale and K Shivkumar and DJ Callans and WG Stevenson and {Della Bella}, P and FE Marchlinski and WH Sauer",

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AU - Tzou, WS

AU - Tung, R

AU - Frankel, DS

AU - Vaseghi, M

AU - Jared Bunch, T

AU - Di Biase, Luigi

AU - Tholakanahalli, VN

AU - Lakkireddy, D

AU - Dickfeld, T

AU - Saliaris, A

AU - Peter Weiss, J

AU - Mathuria, N

AU - Tedrow, U

AU - Afzal, MR

AU - Vergara, P

AU - Nagashima, K

AU - Patel, M

AU - Nakahara, S

AU - Vakil, K

AU - David Burkhardt, J

AU - Tseng, CH

AU - Natale, Andrea

AU - Shivkumar, K

AU - Callans, DJ

AU - Stevenson, WG

AU - Della Bella, P

AU - Marchlinski, FE

AU - Sauer, WH

PY - 2017

Y1 - 2017

N2 - Background - Ventricular tachycardia (VT) radiofrequency ablation has been associated with reduced VT recurrence and mortality, although it is typically not considered among New York Heart Association class IV (NYHA IV) heart failure patients. We compared characteristics and VT radiofrequency ablation outcomes of those with and without NYHA IV in the International VT Ablation Center Collaboration. Methods and Results - NYHA II-IV patients undergoing VT radiofrequency ablation at 12 international centers were included. Clinical variables, VT recurrence, and mortality were analyzed by NYHA IV status using Kaplan-Meier analysis and Cox proportional hazard models. There were significant differences between NYHA IV (n=111) and NYHA II and III (n=1254) patients: NYHA IV had lower left ventricular ejection fraction; more had diabetes mellitus, kidney disease, cardiac resynchronization implantable cardioverter-defibrillator, and VT storm despite greater antiarrhythmic drug use (P

AB - Background - Ventricular tachycardia (VT) radiofrequency ablation has been associated with reduced VT recurrence and mortality, although it is typically not considered among New York Heart Association class IV (NYHA IV) heart failure patients. We compared characteristics and VT radiofrequency ablation outcomes of those with and without NYHA IV in the International VT Ablation Center Collaboration. Methods and Results - NYHA II-IV patients undergoing VT radiofrequency ablation at 12 international centers were included. Clinical variables, VT recurrence, and mortality were analyzed by NYHA IV status using Kaplan-Meier analysis and Cox proportional hazard models. There were significant differences between NYHA IV (n=111) and NYHA II and III (n=1254) patients: NYHA IV had lower left ventricular ejection fraction; more had diabetes mellitus, kidney disease, cardiac resynchronization implantable cardioverter-defibrillator, and VT storm despite greater antiarrhythmic drug use (P

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