TY - JOUR
T1 - Ventricular tachycardia in non-compaction of left ventricle
T2 - Is this a frequent complication?
AU - Fazio, Giovanni
AU - Corrado, Giovanni
AU - Zachara, Elisabetta
AU - Rapezzi, Carlo
AU - Sulafa, Ali K.
AU - Sutera, Loredana
AU - Pizzuto, Caterina
AU - Stollberger, Claudia
AU - Sormani, Luca
AU - Finsterer, Joseph
AU - Benatar, Abraham
AU - Di Gesaro, Gabriele
AU - Cascio, Caterina
AU - Cangemi, Debora
AU - Cavusoglu, Yuksel
AU - Baumhakel, Magnus
AU - Drago, Fabrizio
AU - Carerj, Scipione
AU - Pipitone, Salvatore
AU - Novo, Salvatore
PY - 2007/4
Y1 - 2007/4
N2 - Background: Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association. Methods and Results: In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring was performed every 6 months for 4 years. Only 11 patients had documented ventricular tachycardia, which was sustained in two cases and non-sustained in nine. In no cases we observed ventricular fibrillation. Conclusions: Non-compaction alone does not seem to be a risk factor for malignant ventricular arrhythmias.
AB - Background: Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association. Methods and Results: In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring was performed every 6 months for 4 years. Only 11 patients had documented ventricular tachycardia, which was sustained in two cases and non-sustained in nine. In no cases we observed ventricular fibrillation. Conclusions: Non-compaction alone does not seem to be a risk factor for malignant ventricular arrhythmias.
KW - Isolated left ventricular non-compaction
KW - Malignant
KW - Ventricular arrhythmias
KW - Ventricular tachycardia
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U2 - 10.1111/j.1540-8159.2007.00706.x
DO - 10.1111/j.1540-8159.2007.00706.x
M3 - Article
C2 - 17437580
AN - SCOPUS:34247100241
VL - 30
SP - 544
EP - 546
JO - PACE - Pacing and Clinical Electrophysiology
JF - PACE - Pacing and Clinical Electrophysiology
SN - 0147-8389
IS - 4
ER -