Ventricular tachycardia in non-compaction of left ventricle: Is this a frequent complication?

Giovanni Fazio, Giovanni Corrado, Elisabetta Zachara, Carlo Rapezzi, Ali K. Sulafa, Loredana Sutera, Caterina Pizzuto, Claudia Stollberger, Luca Sormani, Joseph Finsterer, Abraham Benatar, Gabriele Di Gesaro, Caterina Cascio, Debora Cangemi, Yuksel Cavusoglu, Magnus Baumhakel, Fabrizio Drago, Scipione Carerj, Salvatore Pipitone, Salvatore Novo

Research output: Contribution to journalArticlepeer-review


Background: Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association. Methods and Results: In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring was performed every 6 months for 4 years. Only 11 patients had documented ventricular tachycardia, which was sustained in two cases and non-sustained in nine. In no cases we observed ventricular fibrillation. Conclusions: Non-compaction alone does not seem to be a risk factor for malignant ventricular arrhythmias.

Original languageEnglish
Pages (from-to)544-546
Number of pages3
JournalPACE - Pacing and Clinical Electrophysiology
Issue number4
Publication statusPublished - Apr 2007


  • Isolated left ventricular non-compaction
  • Malignant
  • Ventricular arrhythmias
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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