Ventricular tachycardia in structural heart disease: Mechanisms and non- pharmacologic treatment options

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pharmacological therapy for the treatment of scar related Ventricular Tachycardias (VTs) is hampered by a high recurrence rate and frequent side effects. Percutaneous catheter ablation of VTs is currently an important weapon in the treatment of incessant VT and recurrent episodes of sustained VT. Conventional mapping techniques require ongoing tachycardia. However, in many patients, non-inducibility of VT, poor induction reproducibility, hemodynamic instability and the presence of multiple VTs preclude mapping in tachycardia. To overcome these limitations, new strategies for mapping and ablation in sinus rhythm - substrate mapping strategies - have been developed. Late potentials (LP) are recorded in areas of slow conduction, and recent trials have shown that the identification and abolition of these potentials is an effective substrate mapping technique for VT ablation. In this chapter we will summarize the evidence published in literature about activation and substrate VT mapping.

Original languageEnglish
Title of host publicationTachycardia: Risk Factors, Causes and Treatment Options
PublisherNova Science Publishers, Inc.
Pages265-277
Number of pages13
ISBN (Print)9781634633468, 9781634633031
Publication statusPublished - Oct 1 2014

Keywords

  • Epicardial ablation
  • Substrate mapping
  • Ventricular tachycardia ablation

ASJC Scopus subject areas

  • Medicine(all)

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    Vergara, P., & Bella, P. D. (2014). Ventricular tachycardia in structural heart disease: Mechanisms and non- pharmacologic treatment options. In Tachycardia: Risk Factors, Causes and Treatment Options (pp. 265-277). Nova Science Publishers, Inc..