Verapamil in the prophylaxis of episodic cluster headache: A double- blind study versus placebo

M. Leone, D. D'Amico, F. Frediani, F. Moschiano, L. Grazzi, A. Attanasio, G. Bussone

Research output: Contribution to journalArticlepeer-review

Abstract

The authors performed a double-blind, double-dummy study to compare the efficacy of verapamil with placebo in the prophylaxis of episodic cluster headache. After 5 days' run-in, 15 patients received verapamil (120 mg tid) and 15 received placebo (tid) for 14 days. The authors found a significant reduction in attack frequency and abortive agents consumption in the verapamil group. Side effects were mild. These findings provide objective evidence for the effectiveness of verapamil in episodic cluster headache prophylaxis.

Original languageEnglish
Pages (from-to)1382-1385
Number of pages4
JournalNeurology
Volume54
Issue number6
Publication statusPublished - Mar 28 2000

Keywords

  • Episodic cluster headache
  • Prophylaxis
  • Verapamil

ASJC Scopus subject areas

  • Neuroscience(all)

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