Vertebroplasty using calcium triglyceride bone cement (Kryptonite™) for vertebral compression fractures: A single-centre preliminary study of outcomes at one-year follow-up

Gianluigi Guarnieri, Mario Tecame, Roberto Izzo, Pasquale Vassallo, Angela Sardaro, Francesca Iasiello, Carlo Cavaliere, Mario Muto

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

This study assessed the one-year clinical and radiographic outcomes, in terms of pain-relief, vertebral re-fracture and complications, after vertebroplasty (VP) using a new osteoconductive cement (calcium triglyceride bone cement - Kryptonite™ bone cement, Doctors Research Group Inc., Southbury, CT, USA) to treat osteoporotic vertebral compression fractures. Sixteen consecutive osteoporotic patients (12 women and four men, mean age 68+/-10.5) were treated with VP using Kryptonite™ bone cement for a total of 20 vertebral fractures. All the patients complained of a pain syndrome resistant to medical therapy and all procedures were performed under fluoroscopy control with neuroleptoanalgesia using a monopedicular approach in 12 patients and bipedicular approach in four patients. All patients were studied by MR and MDCT and were evaluated with the visual analogue scale (VAS) and the Oswestry disability index (ODI) before treatment and at one and 12 months after the procedure. A successful outcome was observed in 80% of patients, with a complete resolution of pain. Differences in pre and post treatment VAS and ODI at one-year follow-up were significant (P

Original languageEnglish
Pages (from-to)576-582
Number of pages7
JournalInterventional Neuroradiology
Volume20
Issue number5
DOIs
Publication statusPublished - Sep 1 2014

Fingerprint

Vertebroplasty
Compression Fractures
Triglycerides
Outcome Assessment (Health Care)
Calcium
Visual Analog Scale
Pain
Neuroleptanalgesia
Bone Cements
Fluoroscopy
Kryptonite bone cement
Therapeutics
Research

Keywords

  • Bioactive osteoconductive cement
  • Calcium triglyceride bone cement
  • Leakage rate
  • Vertebral re-fracture
  • Vertebroplasty

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Vertebroplasty using calcium triglyceride bone cement (Kryptonite™) for vertebral compression fractures : A single-centre preliminary study of outcomes at one-year follow-up. / Guarnieri, Gianluigi; Tecame, Mario; Izzo, Roberto; Vassallo, Pasquale; Sardaro, Angela; Iasiello, Francesca; Cavaliere, Carlo; Muto, Mario.

In: Interventional Neuroradiology, Vol. 20, No. 5, 01.09.2014, p. 576-582.

Research output: Contribution to journalArticle

Guarnieri, Gianluigi ; Tecame, Mario ; Izzo, Roberto ; Vassallo, Pasquale ; Sardaro, Angela ; Iasiello, Francesca ; Cavaliere, Carlo ; Muto, Mario. / Vertebroplasty using calcium triglyceride bone cement (Kryptonite™) for vertebral compression fractures : A single-centre preliminary study of outcomes at one-year follow-up. In: Interventional Neuroradiology. 2014 ; Vol. 20, No. 5. pp. 576-582.
@article{67d9c8f7e26444e188102e138b661e7e,
title = "Vertebroplasty using calcium triglyceride bone cement (Kryptonite™) for vertebral compression fractures: A single-centre preliminary study of outcomes at one-year follow-up",
abstract = "This study assessed the one-year clinical and radiographic outcomes, in terms of pain-relief, vertebral re-fracture and complications, after vertebroplasty (VP) using a new osteoconductive cement (calcium triglyceride bone cement - Kryptonite™ bone cement, Doctors Research Group Inc., Southbury, CT, USA) to treat osteoporotic vertebral compression fractures. Sixteen consecutive osteoporotic patients (12 women and four men, mean age 68+/-10.5) were treated with VP using Kryptonite™ bone cement for a total of 20 vertebral fractures. All the patients complained of a pain syndrome resistant to medical therapy and all procedures were performed under fluoroscopy control with neuroleptoanalgesia using a monopedicular approach in 12 patients and bipedicular approach in four patients. All patients were studied by MR and MDCT and were evaluated with the visual analogue scale (VAS) and the Oswestry disability index (ODI) before treatment and at one and 12 months after the procedure. A successful outcome was observed in 80{\%} of patients, with a complete resolution of pain. Differences in pre and post treatment VAS and ODI at one-year follow-up were significant (P",
keywords = "Bioactive osteoconductive cement, Calcium triglyceride bone cement, Leakage rate, Vertebral re-fracture, Vertebroplasty",
author = "Gianluigi Guarnieri and Mario Tecame and Roberto Izzo and Pasquale Vassallo and Angela Sardaro and Francesca Iasiello and Carlo Cavaliere and Mario Muto",
year = "2014",
month = "9",
day = "1",
doi = "10.15274/INR-2014-10060",
language = "English",
volume = "20",
pages = "576--582",
journal = "Interventional Neuroradiology",
issn = "1591-0199",
publisher = "Centauro srl",
number = "5",

}

TY - JOUR

T1 - Vertebroplasty using calcium triglyceride bone cement (Kryptonite™) for vertebral compression fractures

T2 - A single-centre preliminary study of outcomes at one-year follow-up

AU - Guarnieri, Gianluigi

AU - Tecame, Mario

AU - Izzo, Roberto

AU - Vassallo, Pasquale

AU - Sardaro, Angela

AU - Iasiello, Francesca

AU - Cavaliere, Carlo

AU - Muto, Mario

PY - 2014/9/1

Y1 - 2014/9/1

N2 - This study assessed the one-year clinical and radiographic outcomes, in terms of pain-relief, vertebral re-fracture and complications, after vertebroplasty (VP) using a new osteoconductive cement (calcium triglyceride bone cement - Kryptonite™ bone cement, Doctors Research Group Inc., Southbury, CT, USA) to treat osteoporotic vertebral compression fractures. Sixteen consecutive osteoporotic patients (12 women and four men, mean age 68+/-10.5) were treated with VP using Kryptonite™ bone cement for a total of 20 vertebral fractures. All the patients complained of a pain syndrome resistant to medical therapy and all procedures were performed under fluoroscopy control with neuroleptoanalgesia using a monopedicular approach in 12 patients and bipedicular approach in four patients. All patients were studied by MR and MDCT and were evaluated with the visual analogue scale (VAS) and the Oswestry disability index (ODI) before treatment and at one and 12 months after the procedure. A successful outcome was observed in 80% of patients, with a complete resolution of pain. Differences in pre and post treatment VAS and ODI at one-year follow-up were significant (P

AB - This study assessed the one-year clinical and radiographic outcomes, in terms of pain-relief, vertebral re-fracture and complications, after vertebroplasty (VP) using a new osteoconductive cement (calcium triglyceride bone cement - Kryptonite™ bone cement, Doctors Research Group Inc., Southbury, CT, USA) to treat osteoporotic vertebral compression fractures. Sixteen consecutive osteoporotic patients (12 women and four men, mean age 68+/-10.5) were treated with VP using Kryptonite™ bone cement for a total of 20 vertebral fractures. All the patients complained of a pain syndrome resistant to medical therapy and all procedures were performed under fluoroscopy control with neuroleptoanalgesia using a monopedicular approach in 12 patients and bipedicular approach in four patients. All patients were studied by MR and MDCT and were evaluated with the visual analogue scale (VAS) and the Oswestry disability index (ODI) before treatment and at one and 12 months after the procedure. A successful outcome was observed in 80% of patients, with a complete resolution of pain. Differences in pre and post treatment VAS and ODI at one-year follow-up were significant (P

KW - Bioactive osteoconductive cement

KW - Calcium triglyceride bone cement

KW - Leakage rate

KW - Vertebral re-fracture

KW - Vertebroplasty

UR - http://www.scopus.com/inward/record.url?scp=84930021447&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930021447&partnerID=8YFLogxK

U2 - 10.15274/INR-2014-10060

DO - 10.15274/INR-2014-10060

M3 - Article

AN - SCOPUS:84930021447

VL - 20

SP - 576

EP - 582

JO - Interventional Neuroradiology

JF - Interventional Neuroradiology

SN - 1591-0199

IS - 5

ER -