Vertical ridge augmentation by expanded-polytetrafluoroethylene membrane and a combination of intraoral autogenous bone graft and deproteinized anorganic bovine bone (Bio Oss)

Massimo Simion, Filippo Fontana, Giulio Rasperini, Carlo Maiorana

Research output: Contribution to journalArticle

Abstract

Objective: To evaluate, from a histological and histomorphometrical perspective, the efficacy of a 1 : 1 mixture of deproteinized bovine bone mineral (DBBM) and autogenous bone graft associated with an expanded- polytetrafluoroethylene (e-PTFE) membrane for vertical ridge augmentation in the human. Material and methods: Seven patients with 10 surgical sites requiring vertical ridge augmentation of partially edentulous lower jaws were included in the study. The vertical augmentation procedure was performed combining a titanium-reinforced e-PTFE Gore-Tex membrane with a composite graft consisting of a 1 : 1 ratio of DBBM (Bio-Oss) and autogenous bone. Twenty-seven Branemark implants have been inserted. Eleven biopsies from the regenerated area were analyzed histologically and histomorphometrically. Results: The healing period was uneventful in nine surgical sites. In one site the membrane showed an exposure after 3 months. At the abutment connection, all implants appeared stable and submerged by a hard regenerated tissue clinically similar to bone. The histological analysis showed new bone formation and ongoing remodelling of the autogenous bone and the DBBM particles. Conclusions: The findings from the present clinical and histological study support the use of a 1 : 1 combination of DBBM and autogenous bone chips for vertical ridge augmentation by means of guided bone regeneration techniques. The regenerated bone may lead to proper osseointegration of a dental implant inserted at the time of the regenerative procedure or after a healing period of at least 6 months. DBBM undergoes very slow resorption and substitution with new bone. Furthermore, long-term clinical studies are needed to confirm the positive effect of DBBM in enhancing the lasting stability of the vertically augmented bone.

Original languageEnglish
Pages (from-to)620-629
Number of pages10
JournalClinical Oral Implants Research
Volume18
Issue number5
DOIs
Publication statusPublished - Oct 2007

Fingerprint

Polytetrafluoroethylene
Transplants
Bone and Bones
Membranes
Minerals
Bio-Oss
Jaw, Edentulous, Partially
Osseointegration
Bone Regeneration
Dental Implants
Bone Remodeling
Titanium
Osteogenesis

Keywords

  • Autogenous bone
  • Barrier membranes
  • Deproteinized bovine bone
  • Guided bone regeneration
  • Osseointegration
  • Vertical ridge augmentation

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Vertical ridge augmentation by expanded-polytetrafluoroethylene membrane and a combination of intraoral autogenous bone graft and deproteinized anorganic bovine bone (Bio Oss). / Simion, Massimo; Fontana, Filippo; Rasperini, Giulio; Maiorana, Carlo.

In: Clinical Oral Implants Research, Vol. 18, No. 5, 10.2007, p. 620-629.

Research output: Contribution to journalArticle

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