Abstract
Objective: To evaluate, from a histological and histomorphometrical perspective, the efficacy of a 1 : 1 mixture of deproteinized bovine bone mineral (DBBM) and autogenous bone graft associated with an expanded- polytetrafluoroethylene (e-PTFE) membrane for vertical ridge augmentation in the human. Material and methods: Seven patients with 10 surgical sites requiring vertical ridge augmentation of partially edentulous lower jaws were included in the study. The vertical augmentation procedure was performed combining a titanium-reinforced e-PTFE Gore-Tex membrane with a composite graft consisting of a 1 : 1 ratio of DBBM (Bio-Oss) and autogenous bone. Twenty-seven Branemark implants have been inserted. Eleven biopsies from the regenerated area were analyzed histologically and histomorphometrically. Results: The healing period was uneventful in nine surgical sites. In one site the membrane showed an exposure after 3 months. At the abutment connection, all implants appeared stable and submerged by a hard regenerated tissue clinically similar to bone. The histological analysis showed new bone formation and ongoing remodelling of the autogenous bone and the DBBM particles. Conclusions: The findings from the present clinical and histological study support the use of a 1 : 1 combination of DBBM and autogenous bone chips for vertical ridge augmentation by means of guided bone regeneration techniques. The regenerated bone may lead to proper osseointegration of a dental implant inserted at the time of the regenerative procedure or after a healing period of at least 6 months. DBBM undergoes very slow resorption and substitution with new bone. Furthermore, long-term clinical studies are needed to confirm the positive effect of DBBM in enhancing the lasting stability of the vertically augmented bone.
| Original language | English |
|---|---|
| Pages (from-to) | 620-629 |
| Number of pages | 10 |
| Journal | Clinical Oral Implants Research |
| Volume | 18 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2007 |
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Keywords
- Autogenous bone
- Barrier membranes
- Deproteinized bovine bone
- Guided bone regeneration
- Osseointegration
- Vertical ridge augmentation
ASJC Scopus subject areas
- Dentistry(all)
Cite this
Vertical ridge augmentation by expanded-polytetrafluoroethylene membrane and a combination of intraoral autogenous bone graft and deproteinized anorganic bovine bone (Bio Oss). / Simion, Massimo; Fontana, Filippo; Rasperini, Giulio; Maiorana, Carlo.
In: Clinical Oral Implants Research, Vol. 18, No. 5, 10.2007, p. 620-629.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vertical ridge augmentation by expanded-polytetrafluoroethylene membrane and a combination of intraoral autogenous bone graft and deproteinized anorganic bovine bone (Bio Oss)
AU - Simion, Massimo
AU - Fontana, Filippo
AU - Rasperini, Giulio
AU - Maiorana, Carlo
PY - 2007/10
Y1 - 2007/10
N2 - Objective: To evaluate, from a histological and histomorphometrical perspective, the efficacy of a 1 : 1 mixture of deproteinized bovine bone mineral (DBBM) and autogenous bone graft associated with an expanded- polytetrafluoroethylene (e-PTFE) membrane for vertical ridge augmentation in the human. Material and methods: Seven patients with 10 surgical sites requiring vertical ridge augmentation of partially edentulous lower jaws were included in the study. The vertical augmentation procedure was performed combining a titanium-reinforced e-PTFE Gore-Tex membrane with a composite graft consisting of a 1 : 1 ratio of DBBM (Bio-Oss) and autogenous bone. Twenty-seven Branemark implants have been inserted. Eleven biopsies from the regenerated area were analyzed histologically and histomorphometrically. Results: The healing period was uneventful in nine surgical sites. In one site the membrane showed an exposure after 3 months. At the abutment connection, all implants appeared stable and submerged by a hard regenerated tissue clinically similar to bone. The histological analysis showed new bone formation and ongoing remodelling of the autogenous bone and the DBBM particles. Conclusions: The findings from the present clinical and histological study support the use of a 1 : 1 combination of DBBM and autogenous bone chips for vertical ridge augmentation by means of guided bone regeneration techniques. The regenerated bone may lead to proper osseointegration of a dental implant inserted at the time of the regenerative procedure or after a healing period of at least 6 months. DBBM undergoes very slow resorption and substitution with new bone. Furthermore, long-term clinical studies are needed to confirm the positive effect of DBBM in enhancing the lasting stability of the vertically augmented bone.
AB - Objective: To evaluate, from a histological and histomorphometrical perspective, the efficacy of a 1 : 1 mixture of deproteinized bovine bone mineral (DBBM) and autogenous bone graft associated with an expanded- polytetrafluoroethylene (e-PTFE) membrane for vertical ridge augmentation in the human. Material and methods: Seven patients with 10 surgical sites requiring vertical ridge augmentation of partially edentulous lower jaws were included in the study. The vertical augmentation procedure was performed combining a titanium-reinforced e-PTFE Gore-Tex membrane with a composite graft consisting of a 1 : 1 ratio of DBBM (Bio-Oss) and autogenous bone. Twenty-seven Branemark implants have been inserted. Eleven biopsies from the regenerated area were analyzed histologically and histomorphometrically. Results: The healing period was uneventful in nine surgical sites. In one site the membrane showed an exposure after 3 months. At the abutment connection, all implants appeared stable and submerged by a hard regenerated tissue clinically similar to bone. The histological analysis showed new bone formation and ongoing remodelling of the autogenous bone and the DBBM particles. Conclusions: The findings from the present clinical and histological study support the use of a 1 : 1 combination of DBBM and autogenous bone chips for vertical ridge augmentation by means of guided bone regeneration techniques. The regenerated bone may lead to proper osseointegration of a dental implant inserted at the time of the regenerative procedure or after a healing period of at least 6 months. DBBM undergoes very slow resorption and substitution with new bone. Furthermore, long-term clinical studies are needed to confirm the positive effect of DBBM in enhancing the lasting stability of the vertically augmented bone.
KW - Autogenous bone
KW - Barrier membranes
KW - Deproteinized bovine bone
KW - Guided bone regeneration
KW - Osseointegration
KW - Vertical ridge augmentation
UR - http://www.scopus.com/inward/record.url?scp=34548694731&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548694731&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0501.2007.01389.x
DO - 10.1111/j.1600-0501.2007.01389.x
M3 - Article
C2 - 17877463
AN - SCOPUS:34548694731
VL - 18
SP - 620
EP - 629
JO - Clinical Oral Implants Research
JF - Clinical Oral Implants Research
SN - 0905-7161
IS - 5
ER -