Trasmissione verticale di HGV e storia naturale dell'infezione nei neonati.

Translated title of the contribution: Vertical transmission of HGV and outcome of the infected babies

G. Dal Molin, P. D'Agaro, C. Biagi, F. Petronio, M. Comar, C. Campello

Research output: Contribution to journalArticlepeer-review

Abstract

To assess the risk of HGV mother-to-infant transmission and the clinical outcome of infected babies, we investigated 103 mother-infant couples and followed-up the infected children for 4-72 months. Twenty (19.4%) mothers were HGV-RNA positive and transmission occurred in ten (50%) babies; only one child acquired HGV and HCV infection. Maternal factors, such as history of intravenous drug use, HCV-RNA positivity, HIV coinfection, type of delivery and type of feeding were not related to HGV transmission. One HGV infected baby showed a mild hepatitis when he was also infected by Cytomegalovirus. Two babies cleared HGV within the first year of life. The HGV transmission rate is elevated but HGV infection seems to be benign, at least in a short-term follow-up.

Translated title of the contributionVertical transmission of HGV and outcome of the infected babies
Original languageItalian
Pages (from-to)109-114
Number of pages6
JournalAnnali di igiene : medicina preventiva e di comunità
Volume16
Issue number1-2
Publication statusPublished - 2004

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