Abstract
Thymectomy without stemotomy was performed by bilateral VATET in 101 MG patients. The histological evaluation revealed a thymoma in 20.89? of cases, an hyperplastic thymus in 48.5% and an involuted thymus in 30.7%. Fifty-seven (56.4%) of our patients had a follow-up of at least 1 year; 30 (29.7%) patients up to 2 years. Comparison of tissue removed by VATET or standard transternal thymectomy showed significant differences in all cases (55.6 ±38.2 vs. 35.54 ±35 grams, p = 0.001) or in only those without thymoma (43.6 ±21.5 vs. 26.3 ±23.5 grams, p = 0.0001) (unpaired r-Test). In the VATET patients the clinical conditions were detected at the end of follow-up: remission, 23.3%; pharmacological remission, 41.7%; ocular, 6.7%: generalized, 23.3%; bulbar, 5% compared to 1.7, 30, 13.3, 45 and 10%, respectively, before thymectomy. No complication occured immediately after or later on in the follow-up. On the basis of these results VATET technique is proposed as a safe, reliable and even more radical thymectomy for MG treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 22 |
| Number of pages | 1 |
| Journal | Italian Journal of Neurological Sciences |
| Volume | 18 |
| Issue number | 4 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Video assisted thoracoscopic extended thymectomy (VATET) in Myasthenia Gravis : 101 patients followed-up to 2 years and comparison with transternal approach. / Mantegazza, R.; Confalonieri, P.; Aniozzi, C.; Novellino, L.; Ferrè, M. T.; Porta, M.; Pezzuoli, G.; Cornelio, F.
In: Italian Journal of Neurological Sciences, Vol. 18, No. 4, 1997, p. 22.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Video assisted thoracoscopic extended thymectomy (VATET) in Myasthenia Gravis
T2 - 101 patients followed-up to 2 years and comparison with transternal approach
AU - Mantegazza, R.
AU - Confalonieri, P.
AU - Aniozzi, C.
AU - Novellino, L.
AU - Ferrè, M. T.
AU - Porta, M.
AU - Pezzuoli, G.
AU - Cornelio, F.
PY - 1997
Y1 - 1997
N2 - Thymectomy without stemotomy was performed by bilateral VATET in 101 MG patients. The histological evaluation revealed a thymoma in 20.89? of cases, an hyperplastic thymus in 48.5% and an involuted thymus in 30.7%. Fifty-seven (56.4%) of our patients had a follow-up of at least 1 year; 30 (29.7%) patients up to 2 years. Comparison of tissue removed by VATET or standard transternal thymectomy showed significant differences in all cases (55.6 ±38.2 vs. 35.54 ±35 grams, p = 0.001) or in only those without thymoma (43.6 ±21.5 vs. 26.3 ±23.5 grams, p = 0.0001) (unpaired r-Test). In the VATET patients the clinical conditions were detected at the end of follow-up: remission, 23.3%; pharmacological remission, 41.7%; ocular, 6.7%: generalized, 23.3%; bulbar, 5% compared to 1.7, 30, 13.3, 45 and 10%, respectively, before thymectomy. No complication occured immediately after or later on in the follow-up. On the basis of these results VATET technique is proposed as a safe, reliable and even more radical thymectomy for MG treatment.
AB - Thymectomy without stemotomy was performed by bilateral VATET in 101 MG patients. The histological evaluation revealed a thymoma in 20.89? of cases, an hyperplastic thymus in 48.5% and an involuted thymus in 30.7%. Fifty-seven (56.4%) of our patients had a follow-up of at least 1 year; 30 (29.7%) patients up to 2 years. Comparison of tissue removed by VATET or standard transternal thymectomy showed significant differences in all cases (55.6 ±38.2 vs. 35.54 ±35 grams, p = 0.001) or in only those without thymoma (43.6 ±21.5 vs. 26.3 ±23.5 grams, p = 0.0001) (unpaired r-Test). In the VATET patients the clinical conditions were detected at the end of follow-up: remission, 23.3%; pharmacological remission, 41.7%; ocular, 6.7%: generalized, 23.3%; bulbar, 5% compared to 1.7, 30, 13.3, 45 and 10%, respectively, before thymectomy. No complication occured immediately after or later on in the follow-up. On the basis of these results VATET technique is proposed as a safe, reliable and even more radical thymectomy for MG treatment.
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M3 - Article
VL - 18
SP - 22
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -