TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI

Translated title of the contribution: Vigabatrin therapy: Tolerability in 32 adult patients

M. T. Faedda, A. T. Giallonardo, P. Quarato, A. Francia, A. Iudice, S. Fabri, M. Manfredi

Research output: Contribution to journalArticle

Abstract

Thirtytwo adult patients (16 females and 16 males, aged from 20 to 59 years) with refractory partial epilepsy entered a single blind study with Vigabatrin (VGB) as add on therapy. There were 19 drop outs. Thirteen patients continued the study, with a follow up of 6 years in 7 and of 3 years in 6. The number of seizures decreased by 100% in one patient, by 70 to 83.3% in four patients, by 50 to 64.28% in three patients and by 50% in five. The side effects were: drowsiness (13 pt), weight gain or appetite (12 pt), oedema (8 pt), sual disturbances (4 pt), appetite gain (3 pt), constipation (3 pt), ataxia (2 pt), delusional episode (1 pt), gastralgia (1 pt).

Translated title of the contributionVigabatrin therapy: Tolerability in 32 adult patients
Original languageItalian
Pages (from-to)271-272
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number79-80
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Clinical Neurology

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    Faedda, M. T., Giallonardo, A. T., Quarato, P., Francia, A., Iudice, A., Fabri, S., & Manfredi, M. (1992). TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI. Bollettino - Lega Italiana contro l'Epilessia, (79-80), 271-272.