Viral antibodies in multiple sclerosis

P. Ferrante, D. Caputo, S. Barbesti, M. Fasan

Research output: Contribution to journalArticlepeer-review

Abstract

The sera of 176 MS patients and of 150 healthy adult controls were assayed for antibodies against mumps, rubella, Sendai and herpes simplex viruses, a higher prevalence of measles c.f.a. having already been demonstrated in the MS patients. The CSF of 48 of the MS patients were subjected to the same tests. The patients differed from the controls in a higher prevalence of h.i.a. to mumps and of c.f.a. to herpes simplex. For the latter, but not for the former, the prevalence was statistically higher only in patients treated with immunosuppressants. To date measles seems to be the most seriously incriminated virus in the etiopathogenesis of MS, mumps ranking second.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalItalian Journal of Neurological Sciences
Volume3
Issue number2
DOIs
Publication statusPublished - Jun 1982

Keywords

  • Multiple sclerosis
  • viral antibodies

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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