Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure

Paola Costenaro, Rebecca Lundin, Maria Raffaella Petrara, Martina Penazzato, William Massavon, Susan Kizito, Sandra Monica Nabachwa, Maria Nannyonga Musoke, Charles Namisi, Erika Morelli, Davide Bilardi, Antonio Mazza, Marisa Zanchetta, Carlo Giaquinto, Anita De Rossi

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Abstract

Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.

Original languageEnglish
Pages (from-to)2665-2667
Number of pages3
JournalJournal of Clinical Microbiology
Volume52
Issue number7
DOIs
Publication statusPublished - 2014

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ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Costenaro, P., Lundin, R., Petrara, M. R., Penazzato, M., Massavon, W., Kizito, S., Nabachwa, S. M., Musoke, M. N., Namisi, C., Morelli, E., Bilardi, D., Mazza, A., Zanchetta, M., Giaquinto, C., & De Rossi, A. (2014). Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure. Journal of Clinical Microbiology, 52(7), 2665-2667. https://doi.org/10.1128/JCM.00961-14