Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure

Paola Costenaro; Rebecca Lundin; Maria Raffaella Petrara; Martina Penazzato; William Massavon; Susan Kizito; Sandra Monica Nabachwa; Maria Nannyonga Musoke; Charles Namisi; Erika Morelli; Davide Bilardi; Antonio Mazza; Marisa Zanchetta; Carlo Giaquinto; Anita De Rossi

doi:10.1128/JCM.00961-14

Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure

Paola Costenaro, Rebecca Lundin, Maria Raffaella Petrara, Martina Penazzato, William Massavon, Susan Kizito, Sandra Monica Nabachwa, Maria Nannyonga Musoke, Charles Namisi, Erika Morelli, Davide Bilardi, Antonio Mazza, Marisa Zanchetta, Carlo Giaquinto, Anita De Rossi

Istituto Oncologico Veneto

Research output: Contribution to journal › Article

Abstract

Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.

Original language	English
Pages (from-to)	2665-2667
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	52
Issue number	7
DOIs	https://doi.org/10.1128/JCM.00961-14
Publication status	Published - 2014

Fingerprint

ASJC Scopus subject areas

Microbiology (medical)

Cite this

Costenaro, P., Lundin, R., Petrara, M. R., Penazzato, M., Massavon, W., Kizito, S., Nabachwa, S. M., Musoke, M. N., Namisi, C., Morelli, E., Bilardi, D., Mazza, A., Zanchetta, M., Giaquinto, C., & De Rossi, A. (2014). Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure. Journal of Clinical Microbiology, 52(7), 2665-2667. https://doi.org/10.1128/JCM.00961-14

Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda : Correlations with clinical and immunological criteria for treatment failure. / Costenaro, Paola; Lundin, Rebecca; Petrara, Maria Raffaella; Penazzato, Martina; Massavon, William; Kizito, Susan; Nabachwa, Sandra Monica; Musoke, Maria Nannyonga; Namisi, Charles; Morelli, Erika; Bilardi, Davide; Mazza, Antonio; Zanchetta, Marisa; Giaquinto, Carlo; De Rossi, Anita.

In: Journal of Clinical Microbiology, Vol. 52, No. 7, 2014, p. 2665-2667.

Research output: Contribution to journal › Article

Costenaro, P, Lundin, R, Petrara, MR, Penazzato, M, Massavon, W, Kizito, S, Nabachwa, SM, Musoke, MN, Namisi, C, Morelli, E, Bilardi, D, Mazza, A, Zanchetta, M, Giaquinto, C & De Rossi, A 2014, 'Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure', Journal of Clinical Microbiology, vol. 52, no. 7, pp. 2665-2667. https://doi.org/10.1128/JCM.00961-14

Costenaro, Paola ; Lundin, Rebecca ; Petrara, Maria Raffaella ; Penazzato, Martina ; Massavon, William ; Kizito, Susan ; Nabachwa, Sandra Monica ; Musoke, Maria Nannyonga ; Namisi, Charles ; Morelli, Erika ; Bilardi, Davide ; Mazza, Antonio ; Zanchetta, Marisa ; Giaquinto, Carlo ; De Rossi, Anita. / Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda : Correlations with clinical and immunological criteria for treatment failure. In: Journal of Clinical Microbiology. 2014 ; Vol. 52, No. 7. pp. 2665-2667.

@article{fbd439dda0e744c0b3615a9a29afebcd,

title = "Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda: Correlations with clinical and immunological criteria for treatment failure",

abstract = "Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.",

author = "Paola Costenaro and Rebecca Lundin and Petrara, {Maria Raffaella} and Martina Penazzato and William Massavon and Susan Kizito and Nabachwa, {Sandra Monica} and Musoke, {Maria Nannyonga} and Charles Namisi and Erika Morelli and Davide Bilardi and Antonio Mazza and Marisa Zanchetta and Carlo Giaquinto and {De Rossi}, Anita",

year = "2014",

doi = "10.1128/JCM.00961-14",

language = "English",

volume = "52",

pages = "2665--2667",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "7",

}

TY - JOUR

T1 - Viral load detection using dried blood spots in a cohort of HIV-1- infected children in uganda

T2 - Correlations with clinical and immunological criteria for treatment failure

AU - Costenaro, Paola

AU - Lundin, Rebecca

AU - Petrara, Maria Raffaella

AU - Penazzato, Martina

AU - Massavon, William

AU - Kizito, Susan

AU - Nabachwa, Sandra Monica

AU - Musoke, Maria Nannyonga

AU - Namisi, Charles

AU - Morelli, Erika

AU - Bilardi, Davide

AU - Mazza, Antonio

AU - Zanchetta, Marisa

AU - Giaquinto, Carlo

AU - De Rossi, Anita

PY - 2014

Y1 - 2014

N2 - Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.

AB - Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.

UR - http://www.scopus.com/inward/record.url?scp=84902764610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902764610&partnerID=8YFLogxK

U2 - 10.1128/JCM.00961-14

DO - 10.1128/JCM.00961-14

M3 - Article

C2 - 24789197

AN - SCOPUS:84902764610

VL - 52

SP - 2665

EP - 2667

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 7

ER -

Access to Document

10.1128/JCM.00961-14