Viral vector approaches to modify gene expression in the brain

Alessandro Papale, Milica Cerovic, Riccardo Brambilla

Research output: Contribution to journalArticle

Abstract

The use of viral vectors as gene transfer tools for the central nervous system has seen a significant growth in the last decade. Improvements in the safety, efficiency and specificity of vectors for clinical applications have proven to be beneficial also for basic neuroscience research. This review will discuss the viral systems currently available to neuroscientists and some of the recent achievements in the study of synaptic function, memory and drug addiction.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalJournal of Neuroscience Methods
Volume185
Issue number1
DOIs
Publication statusPublished - Dec 15 2009

Keywords

  • AMPAR
  • CREB
  • Drug addiction
  • Learning and memory
  • Synaptic plasticity
  • Viral vectors

ASJC Scopus subject areas

  • Neuroscience(all)

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