Impiego dell'endoscopia virtuale con Tomografia computerizzata nell'identificazione delle neoplasie colorettali: Studio prospettico in pazienti sintomatici

Translated title of the contribution: Virtual colonoscopy (CT colonography) in the identification of colorectal cancer: A prospective study in symptomatic patients

Daniele Regge, Giovanni Galatola, Laura Martincich, Teresa Gallo, Massimo Pollone, Antonella Rivolta, Paola Secreto, Angelo Pera

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction. Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. Material and methods. We examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed ex ploration of the entire colon. Results. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. There were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher (85.7%) for polyps ≥1 cm. Conclusions. Virtual colonoscopy is an imaging modality with good diagnostic yield, well tolerated by patients and with great potentials for further development. We suggest that the examination be performed in symptomatic patients who cannot undergo total colonoscopy or refuse the other imaging modalities. Further studies are warranted in larger series of patients, possibly introducing it in screening programs.

Translated title of the contributionVirtual colonoscopy (CT colonography) in the identification of colorectal cancer: A prospective study in symptomatic patients
Original languageItalian
Pages (from-to)449-455
Number of pages7
JournalRadiologia Medica
Volume99
Issue number6
Publication statusPublished - Jun 2000

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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