Virulence genes profile and typing of ovine Pasteureila multocida

J. Shayegh, S. Atashpaz, M. S. Hejazi

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

To learn more about the virulence of Pasteurella multocida isolated from sheep, phenotype, capsular type and some virulence factors (Pfha1, HgbB, TbPA and ToxA) of ovine Pasteurella multocida is described in this study. Forty seven isolates of Pasteurella multocida were isolated from clinically healthy and diseased sheep. The isolates belonged tobiovars 2(4.25%), 3(21.27%), 4(19.14%), 5(2.1%), 6(27.65%), 7(23.4%) and 11(2.1%). Capsular typing of isolates by PCR demonstrated two capsular types A (39), D (3) including 5 untyped with 83.3%, 6.3% and 10.6% prevalence, respectively. Among 4 virulence genes detected by PCR we found a remarkable high prevalence of TbPA (69.4%) and ToxA (72.2%) genes in diseased animals. The high prevalence of ToxA and TbPA among diseased sheep may imply to important role of these genes in epidemiological and virulence of P. multocida isolates in sheep. Additionally, The high prevalence of P. multocida type A ToxA(+) in diseased sheep found in this study is noticeable and attribute to important role of P. multocida type A ToxA(+) in respiratory infection among sheep.

Original languageEnglish
Pages (from-to)206-213
Number of pages8
JournalAsian Journal of Animal and Veterinary Advances
Volume3
Issue number4
DOIs
Publication statusPublished - 2008

Fingerprint

Pasteurella multocida
Virulence
Sheep
virulence
Sheep Diseases
sheep
Genes
genes
Polymerase Chain Reaction
Animal Diseases
Virulence Factors
Respiratory Tract Infections
Phenotype
phenotype
infection

Keywords

  • Capsular type
  • Pasteurella multocida
  • Phenotype
  • Sheep
  • Virulence factor

ASJC Scopus subject areas

  • veterinary(all)
  • Animal Science and Zoology

Cite this

Virulence genes profile and typing of ovine Pasteureila multocida. / Shayegh, J.; Atashpaz, S.; Hejazi, M. S.

In: Asian Journal of Animal and Veterinary Advances, Vol. 3, No. 4, 2008, p. 206-213.

Research output: Contribution to journalArticle

Shayegh, J. ; Atashpaz, S. ; Hejazi, M. S. / Virulence genes profile and typing of ovine Pasteureila multocida. In: Asian Journal of Animal and Veterinary Advances. 2008 ; Vol. 3, No. 4. pp. 206-213.
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