Abstract
Objective: Visceral hyperalgesia is commonly observed in irritable bowel syndrome [IBS], a common cause of comorbidity with fibromyalgia syndrome [FMS]. The aim of this study was to evaluate in patients affected by FMS the presence of IBS-like symptoms and of visceral hyperalgesia. Methods: Twenty-seven FMS patients were studied and compared with 32 IBS patients for visceral hyperalgesia by the anorectal balloon distension test. Results: Eighteen [66%] of FMS patients fitted the Rome criteria for IBS. Patients with IBS presented lower than normal thresholds for the sensation of urgency and pain [P <0.05], whereas the sensation of gas present in the rectum and of desire of defecation were not statistically different from normals. On the contrary, patients with FMS, either with or without IBS-like symptoms, presented values similar to normals for all the examined thresholds [P > 0.05]. Conclusions: Our study confirms that IBS symptoms are present in a relevant proportion of FMS patients, and that the majority of IBS patients present a condition of visceral hypersensitivity, as induced by a rectal balloon distension test. Patients with FMS, however, do not present this feature. The reason why FMS patients frequently have IBS-like symptoms with a normal visceral hypersensitivity remains elusive.
| Original language | English |
|---|---|
| Pages (from-to) | 47-55 |
| Number of pages | 9 |
| Journal | Journal of Musculoskeletal Pain |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2001 |
Fingerprint
Keywords
- Fibromyalgia syndrome
- Irritable bowel syndrome
- Visceral hypersensitivity
ASJC Scopus subject areas
- Rheumatology
- Health Professions(all)
Cite this
Visceral hypersensitivity is not a feature of fibromyalgia syndrome. / Pace, Fabio; Sarzi-Puttini, Piercarlo; Manzionna, Guendalina; Molteni, Paola; Turiel, Maurizio; Panni, Benedetta; Bianchi-Porro, Gabriele.
In: Journal of Musculoskeletal Pain, Vol. 9, No. 1, 2001, p. 47-55.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Visceral hypersensitivity is not a feature of fibromyalgia syndrome
AU - Pace, Fabio
AU - Sarzi-Puttini, Piercarlo
AU - Manzionna, Guendalina
AU - Molteni, Paola
AU - Turiel, Maurizio
AU - Panni, Benedetta
AU - Bianchi-Porro, Gabriele
PY - 2001
Y1 - 2001
N2 - Objective: Visceral hyperalgesia is commonly observed in irritable bowel syndrome [IBS], a common cause of comorbidity with fibromyalgia syndrome [FMS]. The aim of this study was to evaluate in patients affected by FMS the presence of IBS-like symptoms and of visceral hyperalgesia. Methods: Twenty-seven FMS patients were studied and compared with 32 IBS patients for visceral hyperalgesia by the anorectal balloon distension test. Results: Eighteen [66%] of FMS patients fitted the Rome criteria for IBS. Patients with IBS presented lower than normal thresholds for the sensation of urgency and pain [P <0.05], whereas the sensation of gas present in the rectum and of desire of defecation were not statistically different from normals. On the contrary, patients with FMS, either with or without IBS-like symptoms, presented values similar to normals for all the examined thresholds [P > 0.05]. Conclusions: Our study confirms that IBS symptoms are present in a relevant proportion of FMS patients, and that the majority of IBS patients present a condition of visceral hypersensitivity, as induced by a rectal balloon distension test. Patients with FMS, however, do not present this feature. The reason why FMS patients frequently have IBS-like symptoms with a normal visceral hypersensitivity remains elusive.
AB - Objective: Visceral hyperalgesia is commonly observed in irritable bowel syndrome [IBS], a common cause of comorbidity with fibromyalgia syndrome [FMS]. The aim of this study was to evaluate in patients affected by FMS the presence of IBS-like symptoms and of visceral hyperalgesia. Methods: Twenty-seven FMS patients were studied and compared with 32 IBS patients for visceral hyperalgesia by the anorectal balloon distension test. Results: Eighteen [66%] of FMS patients fitted the Rome criteria for IBS. Patients with IBS presented lower than normal thresholds for the sensation of urgency and pain [P <0.05], whereas the sensation of gas present in the rectum and of desire of defecation were not statistically different from normals. On the contrary, patients with FMS, either with or without IBS-like symptoms, presented values similar to normals for all the examined thresholds [P > 0.05]. Conclusions: Our study confirms that IBS symptoms are present in a relevant proportion of FMS patients, and that the majority of IBS patients present a condition of visceral hypersensitivity, as induced by a rectal balloon distension test. Patients with FMS, however, do not present this feature. The reason why FMS patients frequently have IBS-like symptoms with a normal visceral hypersensitivity remains elusive.
KW - Fibromyalgia syndrome
KW - Irritable bowel syndrome
KW - Visceral hypersensitivity
UR - http://www.scopus.com/inward/record.url?scp=0035723170&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035723170&partnerID=8YFLogxK
U2 - 10.1300/J094v09n01_06
DO - 10.1300/J094v09n01_06
M3 - Article
AN - SCOPUS:0035723170
VL - 9
SP - 47
EP - 55
JO - Journal of Musculoskeletal Pain
JF - Journal of Musculoskeletal Pain
SN - 1058-2452
IS - 1
ER -