Abstract
BACKGROUND: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle. METHODS: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months. RESULTS: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p
| Original language | English |
|---|---|
| Pages (from-to) | 155-160 |
| Number of pages | 6 |
| Journal | La Chirurgia degli organi di movimento |
| Volume | 92 |
| Issue number | 3 |
| Publication status | Published - Dec 2008 |
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ASJC Scopus subject areas
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Viscosupplementation for grade II osteoarthritis of the ankle : a prospective study at 18 months' follow-up. / Luciani, Deianira; Cadossi, Matteo; Tesei, Federico; Chiarello, Eugenio; Giannini, Sandro.
In: La Chirurgia degli organi di movimento, Vol. 92, No. 3, 12.2008, p. 155-160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Viscosupplementation for grade II osteoarthritis of the ankle
T2 - a prospective study at 18 months' follow-up.
AU - Luciani, Deianira
AU - Cadossi, Matteo
AU - Tesei, Federico
AU - Chiarello, Eugenio
AU - Giannini, Sandro
PY - 2008/12
Y1 - 2008/12
N2 - BACKGROUND: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle. METHODS: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months. RESULTS: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p
AB - BACKGROUND: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle. METHODS: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months. RESULTS: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p
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UR - http://www.scopus.com/inward/citedby.url?scp=65449182810&partnerID=8YFLogxK
M3 - Article
C2 - 19067120
AN - SCOPUS:65449182810
VL - 92
SP - 155
EP - 160
JO - Chirurgia degli Organi di Movimento
JF - Chirurgia degli Organi di Movimento
SN - 0009-4749
IS - 3
ER -