Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months' follow-up.

Deianira Luciani, Matteo Cadossi, Federico Tesei, Eugenio Chiarello, Sandro Giannini

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

BACKGROUND: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle. METHODS: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months. RESULTS: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p

Original languageEnglish
Pages (from-to)155-160
Number of pages6
JournalLa Chirurgia degli organi di movimento
Volume92
Issue number3
Publication statusPublished - Dec 2008

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Viscosupplementation
Ankle
Osteoarthritis
Prospective Studies
Intra-Articular Injections
Ankle Joint
Hyaluronic Acid
Pain
Knee Osteoarthritis
Joints

ASJC Scopus subject areas

  • Medicine(all)

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Viscosupplementation for grade II osteoarthritis of the ankle : a prospective study at 18 months' follow-up. / Luciani, Deianira; Cadossi, Matteo; Tesei, Federico; Chiarello, Eugenio; Giannini, Sandro.

In: La Chirurgia degli organi di movimento, Vol. 92, No. 3, 12.2008, p. 155-160.

Research output: Contribution to journalArticle

Luciani, D, Cadossi, M, Tesei, F, Chiarello, E & Giannini, S 2008, 'Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months' follow-up.', La Chirurgia degli organi di movimento, vol. 92, no. 3, pp. 155-160.
Luciani, Deianira ; Cadossi, Matteo ; Tesei, Federico ; Chiarello, Eugenio ; Giannini, Sandro. / Viscosupplementation for grade II osteoarthritis of the ankle : a prospective study at 18 months' follow-up. In: La Chirurgia degli organi di movimento. 2008 ; Vol. 92, No. 3. pp. 155-160.
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