Vision from the right stem

Graziella Pellegrini; Paolo Rama; Michele De Luca

doi:10.1016/j.molmed.2010.10.003

Vision from the right stem

Graziella Pellegrini, Paolo Rama, Michele De Luca

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Cultures of limbal cells are a safe and effective treatment for the destruction of the human cornea owing to chemical burns. The essential feature of the graft is the presence of an adequate number of stem cells, which can be determined by the expression of the p63 transcription factor. Here, we will discuss the general principles defining the rigorous criteria for graftable limbal cultures in light of their clinical performances. Such criteria might prove relevant to the future therapeutic use of any cultured cell type.

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	Trends in Molecular Medicine
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.molmed.2010.10.003
Publication status	Published - Jan 2011

ASJC Scopus subject areas

Molecular Biology
Molecular Medicine
Medicine(all)

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