Vision from the right stem

Graziella Pellegrini, Paolo Rama, Michele De Luca

Research output: Contribution to journalArticle

Abstract

Cultures of limbal cells are a safe and effective treatment for the destruction of the human cornea owing to chemical burns. The essential feature of the graft is the presence of an adequate number of stem cells, which can be determined by the expression of the p63 transcription factor. Here, we will discuss the general principles defining the rigorous criteria for graftable limbal cultures in light of their clinical performances. Such criteria might prove relevant to the future therapeutic use of any cultured cell type.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalTrends in Molecular Medicine
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 2011

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Chemical Burns
Therapeutic Uses
Cornea
Cultured Cells
Transcription Factors
Stem Cells
Cell Culture Techniques
Transplants
Therapeutics

ASJC Scopus subject areas

  • Molecular Biology
  • Molecular Medicine
  • Medicine(all)

Cite this

Vision from the right stem. / Pellegrini, Graziella; Rama, Paolo; De Luca, Michele.

In: Trends in Molecular Medicine, Vol. 17, No. 1, 01.2011, p. 1-7.

Research output: Contribution to journalArticle

Pellegrini, Graziella ; Rama, Paolo ; De Luca, Michele. / Vision from the right stem. In: Trends in Molecular Medicine. 2011 ; Vol. 17, No. 1. pp. 1-7.
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